DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5096 and Gp150

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_477049.2	Gene:	Gp150 / 37549	FlyBaseID:	FBgn0013272	Length:	1076	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	121/522 - (23%)
Similarity:	188/522 - (36%)	Gaps:	163/522 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DETTTTETP--------------------KEKIKVIDSKLCKKCNCYIDTNLLDCSEKLQDWLSA 71
            ||.|.|.:|                    |.|.|..|.|..:..|.....:..|..|.|.|
  Fly   172 DEETVTISPSPKKAKSNPKLQPIVDATITKSKSKSNDQKTKESANDIDSDSQYDYDEGLDD---- 232

  Fly    72 EDWED------LTNG-NVVF-------------KTIN------------------LEHNNLTSVP 98
            :|.||      ||:. .|||             :.:|                  .:..:|....
  Fly   233 DDDEDDAADDLLTDDEQVVFSEDVPCPRFCQCARNVNSYLVATCSRLDMGIQKFGSDITDLVVTN 297

  Fly    99 ILPKY---------------DVENLYLANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDV 148
            :.|||               :|.::.:||..::.:...||..|.||..::|:...|.  ::.||.
  Fly   298 VGPKYPILMGPNFFQNLGLKNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLA--IINPDT 360

  Fly   149 FKG-------PFTVQDFESL---------ENLKTLNLGYNDLHSLDADLFEHIPHIEELVLCSNS 197
            |.|       ..:..|...:         .:::.|:...|:|..|:...|.|:.::..:.|..||
  Fly   361 FVGNKKLRMLTISGNDLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNS 425

  Fly   198 FHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGPRDLEIFIAAGNLFNQLPKALKYAT-N 261
               :.:|.|.|...:..|:.||:||..:.:||..|.:| ..|.|.....|.||   ..|.:.| :
  Fly   426 ---LKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNG-TTLSILHLKYNTFN---GDLHFGTKD 483

  Fly   262 LTSLVLNENPIENLIGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQSLTELILSDNKL---- 322
            |..|.|:.|.|.. :..::|..:..||:|::. .:.:.||.|.:|..|::|..:.||.|.|
  Fly   484 LQQLDLSFNSIVQ-VHHSMFDKMPGLTNLNLK-GNGIKKIQPDSFLTLKNLRHIDLSINDLDQIS 546

  Fly   323 --------------LNEIDEEALSKNVTGGQYLDYPPLEKVY---LNNC---------------- 354
                          ||  |...||:..|.| :|.|.....||   ::||
  Fly   547 GMLFFKNSELDVIRLN--DNPRLSQLPTDG-FLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHL 608

  Fly   355 --------NVSTLPKELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDRINKTTPVLAKDVKCG 411
                    |::.||:|:.....||..|||..|          ||..:.|.|......|.|....|
  Fly   609 TTLKLAWNNINHLPREIFTGLHKLIDLDLSNN----------LITRMDDLIFMDNGELTKLSLAG 663

  Fly   412 GP 413
            .|
  Fly   664 NP 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	97/423 (23%)
		leucine-rich repeat	85..104	CDD:275380	5/51 (10%)
		LRR_8	105..174	CDD:290566	17/84 (20%)
		leucine-rich repeat	105..128	CDD:275380	6/22 (27%)
		leucine-rich repeat	129..163	CDD:275380	8/49 (16%)
		LRR_8	163..222	CDD:290566	15/58 (26%)
		leucine-rich repeat	164..187	CDD:275380	6/22 (27%)
		leucine-rich repeat	188..214	CDD:275380	6/25 (24%)
		leucine-rich repeat	215..238	CDD:275380	9/22 (41%)
		leucine-rich repeat	239..261	CDD:275380	7/22 (32%)
		LRR_8	260..322	CDD:290566	19/62 (31%)
		leucine-rich repeat	262..286	CDD:275380	6/23 (26%)
		leucine-rich repeat	287..311	CDD:275380	8/23 (35%)
		leucine-rich repeat	346..369	CDD:275380	8/49 (16%)
		leucine-rich repeat	370..388	CDD:275380	5/17 (29%)
Gp150	NP_477049.2	LRR_8	317..377	CDD:290566	14/61 (23%)
		leucine-rich repeat	343..366	CDD:275380	7/24 (29%)
		leucine-rich repeat	367..391	CDD:275380	1/23 (4%)
		LRR_RI	<374..619	CDD:238064	62/256 (24%)
		LRR_8	390..450	CDD:290566	17/62 (27%)
		leucine-rich repeat	393..415	CDD:275380	6/21 (29%)
		leucine-rich repeat	416..439	CDD:275380	6/25 (24%)
		leucine-rich repeat	440..483	CDD:275380	16/46 (35%)
		leucine-rich repeat	463..481	CDD:275380	6/20 (30%)
		LRR_8	484..542	CDD:290566	18/59 (31%)
		leucine-rich repeat	484..507	CDD:275380	6/23 (26%)
		leucine-rich repeat	508..531	CDD:275380	8/23 (35%)
		leucine-rich repeat	532..569	CDD:275380	9/38 (24%)
		leucine-rich repeat	556..583	CDD:275380	9/29 (31%)
		leucine-rich repeat	570..607	CDD:275380	8/37 (22%)
		LRR_RI	<586..745	CDD:238064	20/90 (22%)
		LRR_8	606..666	CDD:290566	18/70 (26%)
		leucine-rich repeat	608..631	CDD:275380	4/22 (18%)
		leucine-rich repeat	632..655	CDD:275380	9/32 (28%)
		leucine-rich repeat	656..674	CDD:275380	4/10 (40%)
		leucine-rich repeat	733..745	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100