DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5096 and Lrig3

DIOPT Version :9

Sequence 1:NP_723576.1 Gene:CG5096 / 34410 FlyBaseID:FBgn0032235 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_796126.4 Gene:Lrig3 / 320398 MGIID:2443955 Length:1117 Species:Mus musculus


Alignment Length:482 Identity:103/482 - (21%)
Similarity:181/482 - (37%) Gaps:142/482 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 KSATLA-AAIFCIVLSQVS----------GQTKDETTTTETPKEKIKVIDSKLCKKCNCYIDTNL 58
            ::||.| ..:.|..|.:..          ||..|:......|            ..|:|..|  |
Mouse     7 RAATAALGLLLCAGLGRAGPAGSGGHGAPGQLLDDDAQRPCP------------AACHCLGD--L 57

  Fly    59 LDCSEK--------LQDW-----------------------------LSAEDWEDLTN------- 79
            ||||.:        |..|                             |:..:.|.:.|       
Mouse    58 LDCSRRRLVRLPDPLPAWVTRLDLSHNRLSFIQTSSLSHLQSLQEVKLNNNELETIPNLGSISAN 122

  Fly    80 -------GNVVFK-------------TINLEHNNLTSV-PILPKYDVENLYLANNQIDSISVGAF 123
                   ||.:.|             |::|.:||::.: ...|...::.||:.||::.|:..|.|
Mouse   123 IRQLSLAGNAIDKILPEQLEAFQSLETLDLSNNNISELRTAFPPLQLKYLYINNNRVSSMEPGYF 187

  Fly   124 QNL-TELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDLHSLDADLFEHIPH 187
            .|| :.|:.|.|:.||:::  :.|.:||          |..|:.|.|..|.:.::|...|:.:..
Mouse   188 DNLASTLLVLKLNRNRISA--IPPKMFK----------LPQLQHLELNRNKIKNVDGLTFQGLGA 240

  Fly   188 IEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGPRDLEIFIAAGNLFNQL 252
            ::.|.:..|.   :.:|.:.|..||.::::|.:.:..:.::....|:|...|.....:.|..|::
Mouse   241 LKSLKMQRNG---VTKLMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRI 302

  Fly   253 -PKALKYATNLTSLVLNENPIENL---------------IGDN--------VFPPLTKLTHLSM- 292
             |.|.::...|:.|.|..|.:..|               ||:|        .|..||.|..|.: 
Mouse   303 SPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLR 367

  Fly   293 -TFMSKLYKIGPGAFSELQSLTELILSDNKLLNEIDEEALSKNVTGGQYLDYPPLEKVYLNNCNV 356
             ..:|...:...||||.|..|.:|||..|::          :::|...:.....||.:.|:...:
Mouse   368 NNEISWTIEDMSGAFSGLDRLRQLILQGNRI----------RSITKKAFAGLDTLEHLDLSGNAI 422

  Fly   357 STLPKELLVRWDKLKALDLRFNPWNCD 383
            .:|......:..||:.|.|..:...||
Mouse   423 MSLQSNAFSQMKKLQQLHLNTSSLLCD 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5096NP_723576.1 LRR_RI 69..378 CDD:238064 82/363 (23%)
leucine-rich repeat 85..104 CDD:275380 6/32 (19%)
LRR_8 105..174 CDD:290566 22/69 (32%)
leucine-rich repeat 105..128 CDD:275380 9/23 (39%)
leucine-rich repeat 129..163 CDD:275380 9/33 (27%)
LRR_8 163..222 CDD:290566 13/58 (22%)
leucine-rich repeat 164..187 CDD:275380 6/22 (27%)
leucine-rich repeat 188..214 CDD:275380 6/25 (24%)
leucine-rich repeat 215..238 CDD:275380 3/22 (14%)
leucine-rich repeat 239..261 CDD:275380 5/22 (23%)
LRR_8 260..322 CDD:290566 24/86 (28%)
leucine-rich repeat 262..286 CDD:275380 10/46 (22%)
leucine-rich repeat 287..311 CDD:275380 8/25 (32%)
leucine-rich repeat 346..369 CDD:275380 4/22 (18%)
leucine-rich repeat 370..388 CDD:275380 5/14 (36%)
Lrig3NP_796126.4 LRR 1 75..98 1/22 (5%)
LRR_8 76..133 CDD:290566 5/56 (9%)
leucine-rich repeat 76..99 CDD:275378 0/22 (0%)
LRR_RI 81..324 CDD:238064 53/257 (21%)
LRR 2 99..120 3/20 (15%)
leucine-rich repeat 100..146 CDD:275378 6/45 (13%)
LRR_8 122..179 CDD:290566 12/56 (21%)
LRR 3 122..143 3/20 (15%)
LRR 4 146..168 5/21 (24%)
leucine-rich repeat 147..168 CDD:275380 5/20 (25%)
LRR_8 168..227 CDD:290566 22/70 (31%)
leucine-rich repeat 169..192 CDD:275380 9/22 (41%)
LRR 5 169..189 7/19 (37%)
LRR 6 193..214 8/32 (25%)
leucine-rich repeat 194..216 CDD:275380 9/33 (27%)
LRR_8 215..275 CDD:290566 13/62 (21%)
LRR 7 216..237 6/20 (30%)
leucine-rich repeat 217..240 CDD:275380 6/22 (27%)
LRR 8 240..261 4/23 (17%)
leucine-rich repeat 241..264 CDD:275380 6/25 (24%)
LRR_RI 262..>446 CDD:238064 42/193 (22%)
LRR_8 263..323 CDD:290566 12/59 (20%)
LRR 9 264..285 2/20 (10%)
leucine-rich repeat 265..288 CDD:275380 3/22 (14%)
LRR 10 288..309 5/20 (25%)
leucine-rich repeat 289..312 CDD:275380 5/22 (23%)
LRR_8 312..371 CDD:290566 13/58 (22%)
LRR 11 312..333 5/20 (25%)
leucine-rich repeat 313..336 CDD:275380 5/22 (23%)
LRR 12 336..357 4/20 (20%)
leucine-rich repeat 337..360 CDD:275380 5/22 (23%)
LRR_8 359..422 CDD:290566 18/72 (25%)
LRR 13 360..382 4/21 (19%)
leucine-rich repeat 361..385 CDD:275380 7/23 (30%)
LRR 14 387..408 6/30 (20%)
leucine-rich repeat 388..411 CDD:275380 6/32 (19%)
LRR 15 411..432 4/20 (20%)
leucine-rich repeat 412..433 CDD:275380 4/20 (20%)
LRRCT 446..494 CDD:214507 2/4 (50%)
I-set 499..599 CDD:254352
Ig 500..587 CDD:299845
I-set 603..693 CDD:254352
Ig_1 620..694 CDD:143240
I-set 697..784 CDD:254352
IGc2 711..774 CDD:197706
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1019..1093
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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