DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5096 and Chad

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_062037.1	Gene:	Chad / 29195	RGDID:	2336	Length:	358	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	86/398 - (21%)
Similarity:	146/398 - (36%)	Gaps:	100/398 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KKCNCYIDTNLLDCSEKLQDWLSAEDWEDLTNGNVVFKTINLEHNNLTSVPILPKY------DVE 106
            :.|:|:.|...:.|.:        ...:.:...:...|.:||:.||.   |:|...      ::.
  Rat    24 QNCHCHGDLQHVICDK--------VGLQKIPKVSETTKLLNLQRNNF---PVLAANSFRTVPNLV 77

  Fly   107 NLYLANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGY 171
            :|:|.:..|..::.|||:.|.:|:.|.|||
  Rat    78 SLHLQHCNIREVAAGAFRGLKQLIYLYLSH----------------------------------- 107

  Fly   172 NDLHSLDADLFEHIPHIEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGP 236
            ||:..|.|..|:.:..:..|.|..|.   :.:|....:|.|.:|.||.::..:|.:|......|.
  Rat   108 NDIRVLRAGAFDDLTELTYLYLDHNK---VSELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGA 169

  Fly   237 RDLE-IFIAAGNLFNQLPKALKYATNLTSLVLNENPIENLIGDNVFPPLT----------KLTHL 290
            :||. ::::...|.:..|.:|....||....|:.|.:.:      :|...          ||:|
  Rat   170 KDLRWLYLSENALTSLHPGSLDDVENLAKFHLDRNQLSS------YPSAALSKLRVVEELKLSH- 227

  Fly   291 SMTFMSKLYKIGPGAFSELQSLTELILSDNKLLNEIDEEALSKNVTGGQYLDYPPLEKVYLNNCN 355
                 :.|..|...||.......|.:..||..|.:..:.|.:...|         |:.|:|.|..
  Rat   228 -----NPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDAAFAGVTT---------LKHVHLENNR 278

  Fly   356 VSTLPKELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDRINKTTPVLAKDVKCGGPNK----- 415
            ::.||...  .:|.|:.|.|..|||.|......|...|..:.::      .|..|..|.|
  Rat   279 LNQLPSTF--PFDNLETLTLTNNPWKCTCQLRGLRRWLEAKTSR------PDATCSSPAKFKGQR 335

  Fly   416 LNDVTLLR 423
            :.|...||
  Rat   336 IRDTDALR 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	69/325 (21%)
		leucine-rich repeat	85..104	CDD:275380	7/24 (29%)
		LRR_8	105..174	CDD:290566	13/68 (19%)
		leucine-rich repeat	105..128	CDD:275380	7/22 (32%)
		leucine-rich repeat	129..163	CDD:275380	5/33 (15%)
		LRR_8	163..222	CDD:290566	14/58 (24%)
		leucine-rich repeat	164..187	CDD:275380	5/22 (23%)
		leucine-rich repeat	188..214	CDD:275380	6/25 (24%)
		leucine-rich repeat	215..238	CDD:275380	6/22 (27%)
		leucine-rich repeat	239..261	CDD:275380	4/22 (18%)
		LRR_8	260..322	CDD:290566	15/71 (21%)
		leucine-rich repeat	262..286	CDD:275380	4/33 (12%)
		leucine-rich repeat	287..311	CDD:275380	6/23 (26%)
		leucine-rich repeat	346..369	CDD:275380	6/22 (27%)
		leucine-rich repeat	370..388	CDD:275380	7/17 (41%)
Chad	NP_062037.1	LRRNT	22..48	CDD:279764	4/31 (13%)
		LRR 1	51..72		7/23 (30%)
		leucine-rich repeat	52..75	CDD:275380	7/25 (28%)
		LRR_8	74..134	CDD:290566	20/97 (21%)
		LRR 2	75..96		6/20 (30%)
		leucine-rich repeat	76..99	CDD:275380	7/22 (32%)
		LRR_RI	<89..281	CDD:238064	53/250 (21%)
		LRR 3	99..120		10/55 (18%)
		leucine-rich repeat	100..123	CDD:275380	10/57 (18%)
		LRR 4	123..144		4/23 (17%)
		leucine-rich repeat	124..147	CDD:275380	6/25 (24%)
		LRR_8	147..206	CDD:290566	15/58 (26%)
		LRR 5	147..168		5/20 (25%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		LRR 6	171..192		5/20 (25%)
		leucine-rich repeat	172..195	CDD:275380	4/22 (18%)
		LRR_8	195..255	CDD:290566	15/71 (21%)
		LRR 7	195..216		5/26 (19%)
		leucine-rich repeat	196..219	CDD:275380	4/28 (14%)
		LRR 8	219..240		7/26 (27%)
		leucine-rich repeat	220..243	CDD:275380	7/28 (25%)
		LRR_8	243..300	CDD:290566	16/67 (24%)
		LRR 9	244..265		5/20 (25%)
		leucine-rich repeat	245..268	CDD:275380	5/22 (23%)
		LRR 10	268..289		7/31 (23%)
		LRRCT	299..346	CDD:214507	13/51 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..358		7/23 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D334557at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920