Protein Alignment CG5096 and lron-15

DIOPT Version :10

• Sequence 1: NP_723576.1
• Gene: CG5096 / 34410
• FlyBaseID: FBgn0032235
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_495322.3
• Gene: lron-15 / 174079
• WormBaseID: WBGene00016974
• Length: 1275
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 121/507 - (23%)
• Similarity: 207/507 - (40%)
• Gaps: 130/507 - (25%)

  Fly     1 MNLTKSATLAAAIFCIVLSQVSGQTKDETTTTE-------------------------------- 33
            |:|.|..:|.:.            ||:||:|..
 Worm   444 MSLKKPTSLLSI------------TKEETSTVRRLNLAGNRINNMSDYLIFEHMPLLTYVDVSFN 496

  Fly    34 -----TPK--EKIKVIDS---------------KLCKKCNCYIDTNLLDCSE--------KLQDW 68
                 :|:  ||:|.::|               :|.|..:..:|.|.:...:        |||..
 Worm   497 RIRFISPRVFEKLKNLESLFLQNNQLAHFPSLFRLDKLRHLMLDNNQIQKIDNFSLADLPKLQHL 561

  Fly    69 LSAEDWEDLTNGNVV-------FKTINLEHNNLTSVPILPKYDVENLY---LANNQIDSISVGAF 123
            ..|.:..|:...|:.       .|::||.||.:.|:......|::||.   |::|.|.:|:...|
 Worm   562 SLAGNQLDIITENMFGSSSSSELKSLNLAHNKIHSISSRSFSDLDNLQQLRLSHNNIRTITSMTF 626

  Fly   124 QNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDLHSLDADLFEHIPHI 188
            .||..|..|||||||:. |:|...:::          |..|..|:|.:|:|:.:|.|.|.....:
 Worm   627 SNLRNLRYLDLSHNRII-KILPSALYQ----------LPALDVLHLDHNNLNEIDRDAFRSFSDL 680

  Fly   189 EELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLP-DTILHGPRDLEIFIAAGNLFNQL 252
            :.|.|..|:|.   :.|...:..:..:..||:|..:|:::. ..|..|.|.|.:   |.|...::
 Worm   681 QSLKLSHNAFR---RFSCEFLGSISQVHQLDLSSNQINEIDIFCIARGIRKLSL---ASNSVEKI 739

  Fly   253 -PKALKYATNLTSLVLNENPIENLIGDNVFPPLTKLTH--LSMTFMSKLYKIGPGAFSELQSLTE 314
             .|.|:.||.|||:.::.|.|.::..| .|....||:|  ||..::..|:|   |.|...:||..
 Worm   740 NRKLLQDATELTSIDISHNGIIDVDSD-AFCECRKLSHIKLSHNYIRNLWK---GTFQYQESLHT 800

  Fly   315 LILSDNKLLNEIDEEALSKNVTGGQYLDYPPLEKVYLNNCNVSTLPKELL-VRWDKLKALDLRFN 378
            |.:|.|.:| .:.:....||          .:.::::||..:|.:|.|.| .....|..|||..|
 Worm   801 LDISFNDIL-FLHQGTFGKN----------NILQLHVNNNKLSRIPLEALSSTMASLHLLDLAHN 854

  Fly   379 PWNCDESNDFL----INVLIDRINKTTPVLAKDVKCGGPNKLNDVTLLRVAN 426
            .....:|:...    :::|....||     ...::.|....|..:.:|.::|
 Worm   855 NIKIVDSSQLTSFGNLSILSFANNK-----VDSIEDGAFENLLSLKILDLSN 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR	54..>322	CDD:443914	83/289 (29%)
		leucine-rich repeat	85..104	CDD:275380	6/18 (33%)
		leucine-rich repeat	105..128	CDD:275380	9/25 (36%)
		leucine-rich repeat	129..163	CDD:275380	11/33 (33%)
		leucine-rich repeat	164..187	CDD:275380	8/22 (36%)
		leucine-rich repeat	188..214	CDD:275380	5/25 (20%)
		leucine-rich repeat	215..238	CDD:275380	6/23 (26%)
		leucine-rich repeat	239..261	CDD:275380	6/22 (27%)
		leucine-rich repeat	262..286	CDD:275380	7/23 (30%)
		leucine-rich repeat	287..311	CDD:275380	8/25 (32%)
		leucine-rich repeat	346..369	CDD:275380	6/23 (26%)
		leucine-rich repeat	370..388	CDD:275380	6/17 (35%)
lron-15	NP_495322.3	PLN00113	120..>648	CDD:215061	50/216 (23%)
		leucine-rich repeat	120..144	CDD:275380
		leucine-rich repeat	145..168	CDD:275380
		leucine-rich repeat	169..194	CDD:275380
		leucine-rich repeat	195..217	CDD:275380
		leucine-rich repeat	218..239	CDD:275380
		leucine-rich repeat	240..263	CDD:275380
		leucine-rich repeat	264..311	CDD:275380
		leucine-rich repeat	312..335	CDD:275380
		leucine-rich repeat	336..356	CDD:275380
		leucine-rich repeat	361..383	CDD:275380
		leucine-rich repeat	384..405	CDD:275380
		leucine-rich repeat	409..432	CDD:275380
		LRR	415..840	CDD:443914	107/439 (24%)
		leucine-rich repeat	433..462	CDD:275380	8/29 (28%)
		leucine-rich repeat	463..487	CDD:275380	0/23 (0%)
		leucine-rich repeat	488..511	CDD:275380	3/22 (14%)
		leucine-rich repeat	512..533	CDD:275380	2/20 (10%)
		leucine-rich repeat	534..557	CDD:275380	2/22 (9%)
		leucine-rich repeat	558..581	CDD:275380	5/22 (23%)
		leucine-rich repeat	584..607	CDD:275380	7/22 (32%)
		leucine-rich repeat	608..631	CDD:275380	8/22 (36%)
		leucine-rich repeat	632..655	CDD:275380	11/33 (33%)
		leucine-rich repeat	656..676	CDD:275380	8/19 (42%)
		leucine-rich repeat	680..703	CDD:275380	5/25 (20%)
		leucine-rich repeat	704..749	CDD:275380	13/47 (28%)
		leucine-rich repeat	726..739	CDD:275378	4/15 (27%)
		leucine-rich repeat	750..771	CDD:275380	7/21 (33%)
		leucine-rich repeat	774..797	CDD:275380	8/25 (32%)
		LRR	<791..1089	CDD:443914	28/127 (22%)
		leucine-rich repeat	798..845	CDD:275380	13/57 (23%)
		leucine-rich repeat	846..869	CDD:275380	6/22 (27%)
		leucine-rich repeat	870..893	CDD:275380	5/27 (19%)
		leucine-rich repeat	894..915	CDD:275380	2/8 (25%)
		leucine-rich repeat	940..963	CDD:275380
		leucine-rich repeat	964..987	CDD:275380
		leucine-rich repeat	988..1009	CDD:275380
		leucine-rich repeat	1038..1064	CDD:275380
		leucine-rich repeat	1113..1139	CDD:275380