Protein Alignment CG5096 and lron-11

DIOPT Version :10

• Sequence 1: NP_723576.1
• Gene: CG5096 / 34410
• FlyBaseID: FBgn0032235
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_491035.1
• Gene: lron-11 / 171837
• WormBaseID: WBGene00022129
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 126/495 - (25%)
• Similarity: 203/495 - (41%)
• Gaps: 85/495 - (17%)

  Fly    17 VLSQVSGQTKDETTTTETPK-EKIKVIDSKLCKKCNCYIDTNLLDCSEKLQDWLSAEDWE----- 75
            |:|..|| .|..|.||...| ..::.|...|..:      |.:||.|......|||::..
 Worm    15 VISCQSG-CKCPTKTTAVCKGSSLRSIPILLDPR------TTVLDLSNNRISRLSADELSLYPNL 72

  Fly    76 ---DLTNGNV------VFKT------INLEHNNLTSVP--ILPKY-DVENLYLANNQIDSISVGA 122
               .|.|.::      ||.|      ::|..|:|.|:|  :..|. :::.|.:::|.: .:....
 Worm    73 EQLILHNNSITHLSADVFSTLPSLRVLDLSSNSLLSLPNEVFSKLKNLKTLIISSNDV-QLGPEC 136

  Fly   123 FQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDLHSLDADLFEHIPH 187
            |..|::|.||.::.|||:  .|.|.|.|         .|..|:.|:|..|.|.|:.|.:..::..
 Worm   137 FAGLSQLQTLSIADNRLS--FLPPSVLK---------PLSGLRNLDLSANKLLSMPASVMNNLGG 190

  Fly   188 IEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGPRDLEIFIAAGNLFNQL 252
            :|.|.|..|   ::..|........:.||.||||...|.|:.:..|:|...||......|...:|
 Worm   191 LETLKLKQN---LLSSLETGMFLSQKELKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQLVRL 252

  Fly   253 PKALKYATNLTSLVLNENPIENLIGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQSLTELIL 317
            |........|.:|.|:.|...:|...: |..|..|.:|:::....|..|....|.:|.||..|.:
 Worm   253 PGNTWSLPALKTLDLSSNLFVSLETAS-FDGLPALQYLNISHSRNLKTIQMATFVQLSSLHWLSI 316

  Fly   318 SDNKLLNEIDEEALSKNVTGGQYLDYPPLEKVYLNNCNVSTLPKELLVRWDKLKALDLRFNPWNC 382
            |.:.|          .::....:...|||..:.|:|..:..:...:| :|..::.|.|..|.|:|
 Worm   317 SSSAL----------THIHPSAFNPIPPLSHLDLSNNELRYVAPGML-QWPNIRNLHLANNDWHC 370

  Fly   383 DESNDFLINVLIDRINKTTPVLAKDVKCGGPNKLNDVTLLRVANEHMIESSTGSLIWVGLLVVLL 447
              |.|.       |::...|  ..|.||.||..|....:    ||....|..|.|:...|||:.:
 Worm   371 --SCDL-------RVSNLNP--RDDAKCSGPENLAGAPI----NELSSCSILGGLLIPFLLVLFI 420

  Fly   448 IAVPTIIGAYVMKRRGCFGVFRRHDSGASSALYNRTSFNE 487
            :.:..:|.|...|:            ....:|.||..:|:
 Worm   421 LLLALVILALACKK------------SKPVSLKNRAFYND 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR	54..>322	CDD:443914	77/290 (27%)
		leucine-rich repeat	85..104	CDD:275380	7/27 (26%)
		leucine-rich repeat	105..128	CDD:275380	4/22 (18%)
		leucine-rich repeat	129..163	CDD:275380	11/33 (33%)
		leucine-rich repeat	164..187	CDD:275380	7/22 (32%)
		leucine-rich repeat	188..214	CDD:275380	5/25 (20%)
		leucine-rich repeat	215..238	CDD:275380	10/22 (45%)
		leucine-rich repeat	239..261	CDD:275380	5/21 (24%)
		leucine-rich repeat	262..286	CDD:275380	7/23 (30%)
		leucine-rich repeat	287..311	CDD:275380	6/23 (26%)
		leucine-rich repeat	346..369	CDD:275380	5/22 (23%)
		leucine-rich repeat	370..388	CDD:275380	6/17 (35%)
lron-11	NP_491035.1	LRR	33..368	CDD:443914	91/367 (25%)
		leucine-rich repeat	48..71	CDD:275380	7/22 (32%)
		leucine-rich repeat	72..95	CDD:275380	5/22 (23%)
		leucine-rich repeat	96..119	CDD:275380	6/22 (27%)
		leucine-rich repeat	120..142	CDD:275380	4/22 (18%)
		leucine-rich repeat	143..166	CDD:275380	11/33 (33%)
		leucine-rich repeat	167..190	CDD:275380	7/22 (32%)
		leucine-rich repeat	191..214	CDD:275380	5/25 (20%)
		leucine-rich repeat	215..238	CDD:275380	10/22 (45%)
		leucine-rich repeat	239..261	CDD:275380	5/21 (24%)
		leucine-rich repeat	262..283	CDD:275380	6/21 (29%)
		leucine-rich repeat	286..310	CDD:275380	6/23 (26%)
		leucine-rich repeat	311..334	CDD:275380	4/32 (13%)
		leucine-rich repeat	335..357	CDD:275380	5/22 (23%)