DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5096 and lrrc15

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_031758235.1	Gene:	lrrc15 / 100496322	XenbaseID:	XB-GENE-990725	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	394	Identity:	108/394 - (27%)
Similarity:	180/394 - (45%)	Gaps:	58/394 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SEKLQDWLSAEDWEDLTNGNVVFKTINLEHNNLTSV-PIL--PKYDVENLYLANNQIDSISVGAF 123
            :.|||: |....::||..    .:|:.|.:|.:..: |.|  ...:|::|.:..|.::||.||||
Frog   108 NNKLQE-LHGNLFKDLAK----LETLILSNNQINQIHPSLFTALSNVKDLQMVGNNLESIPVGAF 167

  Fly   124 QNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDLHSLDADLFEHIPHI 188
            ..::.|:.|:|:.|.:  |.|.|         |.|:.|..|:||.|..|.|..:.|...:.:..:
Frog   168 DQMSGLLKLNLAKNSI--KYLPP---------QAFDKLAKLQTLRLYENQLQDIPAGFLKKLSSL 221

  Fly   189 EELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGPRDLEIFIAAGN------ 247
            :|:.|.||.   :.:||....||...|:.:.:|..|||.||..|.....::......||
Frog   222 QEVALHSNK---LIELSTDTFSGNPYLQKVFLSNNEIDSLPRGIFLNLPEITKLTLYGNALRELT 283

  Fly   248 --LFNQLPKALKYATNLTSLVLNENPIENLIGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQ 310
              :|..:||       |..|.|.:|.:|.|. ||||..||: |.|.:...:|:..|...||..|:
Frog   284 TGVFGPMPK-------LKELWLYDNQLEQLT-DNVFSNLTE-TVLLVISKNKIRSISTHAFCGLE 339

  Fly   311 SLTELILSDNKLLNEIDEEALS-----KNVT----------GGQYLDYPPLEKVYLNNCNVSTLP 360
            .|.||.|..| ||..:|::.|.     :|::          |..:.:...:..:.|.|.::..:|
Frog   340 ELQELSLHTN-LLTTLDQDVLKCLPKLQNISLHSNKIQYLPGDLFKNMDTVMNIQLQNNSLEDIP 403

  Fly   361 KELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDRINKTTPVLAKDVKCGGPNKLNDVTLLRVA 425
            .:......:|..:.|..|||.||.:...|.|.|.:.:||... |::.|....|  .|.:.:..::
Frog   404 HDFFDSLVQLNEVKLYENPWKCDHNLLSLKNWLSENMNKLGN-LSQLVCTNSP--FNGIPISELS 465

  Fly   426 NEHM 429
            :|.:
Frog   466 DEQL 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	90/334 (27%)
		leucine-rich repeat	85..104	CDD:275380	5/21 (24%)
		LRR_8	105..174	CDD:290566	24/68 (35%)
		leucine-rich repeat	105..128	CDD:275380	9/22 (41%)
		leucine-rich repeat	129..163	CDD:275380	10/33 (30%)
		LRR_8	163..222	CDD:290566	16/58 (28%)
		leucine-rich repeat	164..187	CDD:275380	7/22 (32%)
		leucine-rich repeat	188..214	CDD:275380	8/25 (32%)
		leucine-rich repeat	215..238	CDD:275380	8/22 (36%)
		leucine-rich repeat	239..261	CDD:275380	5/29 (17%)
		LRR_8	260..322	CDD:290566	24/61 (39%)
		leucine-rich repeat	262..286	CDD:275380	11/23 (48%)
		leucine-rich repeat	287..311	CDD:275380	7/23 (30%)
		leucine-rich repeat	346..369	CDD:275380	3/22 (14%)
		leucine-rich repeat	370..388	CDD:275380	7/17 (41%)
lrrc15	XP_031758235.1	leucine-rich repeat	35..51	CDD:275380
		LRR_8	51..111	CDD:404697	0/2 (0%)
		leucine-rich repeat	54..76	CDD:275380
		leucine-rich repeat	77..100	CDD:275380
		internalin_A	98..>449	CDD:380193	104/370 (28%)
		leucine-rich repeat	101..124	CDD:275380	6/16 (38%)
		leucine-rich repeat	125..148	CDD:275380	5/22 (23%)
		leucine-rich repeat	149..172	CDD:275380	9/22 (41%)
		leucine-rich repeat	173..196	CDD:275380	10/33 (30%)
		leucine-rich repeat	197..220	CDD:275380	7/22 (32%)
		leucine-rich repeat	221..244	CDD:275380	8/25 (32%)
		leucine-rich repeat	245..268	CDD:275380	8/22 (36%)
		leucine-rich repeat	269..292	CDD:275380	3/22 (14%)
		leucine-rich repeat	293..316	CDD:275380	11/23 (48%)
		leucine-rich repeat	317..340	CDD:275380	7/22 (32%)
		leucine-rich repeat	341..362	CDD:275380	9/21 (43%)
		leucine-rich repeat	365..388	CDD:275380	2/22 (9%)
		leucine-rich repeat	389..410	CDD:275380	3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000