DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5096 and si:dkey-182i3.11

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_021322095.1	Gene:	si:dkey-182i3.11 / 100334238	ZFINID:	ZDB-GENE-121214-258	Length:	710	Species:	Danio rerio

Alignment Length:	482	Identity:	121/482 - (25%)
Similarity:	202/482 - (41%)	Gaps:	140/482 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 IDTNLLD-CSEKLQDWLSAEDWEDLTNGN-----------------------VVFKTIN-----L 89
            |:.|:.: |:...:.:||....:.:.||:                       |:.:|.|     |
Zfish   214 IEMNVFENCTYLAKLYLSKNKLKSVGNGSFKGATGLNHLDLGLNGLAGIPTIVLQETSNLTSLYL 278

  Fly    90 EHNNLTSVP------ILPKYDVENLYLANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDV 148
            :.|::||:|      ||   .:::|.|:.|.:.|||.|:|::|::||.||||.|:|.:
Zfish   279 QKNDITSIPDNVFSEIL---SLKHLDLSYNGLVSISNGSFRSLSQLVYLDLSFNQLQT------- 333

  Fly   149 FKGPFTVQDFESLENLKTLNLGYNDLHSLDADLFEHIPHIEELVLCSNSFHVID----------- 202
                .|...||.|..|:.|||.:|.|.||..::|:::..::||.|.||:..||.
Zfish   334 ----LTQHVFEDLGKLENLNLYHNKLTSLPNNMFKNLTMLKELQLDSNNISVIPPDLFHPLSALK 394

  Fly   203 --QLSETAISGLQS--------LKILDVSYMEIDDLPDTILH-GPRDLEI------FIAA----- 245
              ||....||.|.|        ||.||:|..::..:|:.:.| ..::|.:      ||:.
Zfish   395 DLQLDNNHISKLHSHTFKKLRQLKQLDISSNDLTKIPNHLFHKNLKELNLENNHISFISKFSFKN 459

  Fly   246 -----------GNLFNQLPKALKYATNLTSLVLNENPIENL-----------------------I 276
                       .||.....:.|...|.|..|:||||.||.:                       |
Zfish   460 LHRLQSLKLSHNNLSKLYRELLTNLTRLRELLLNENQIETIPVGFFKGLENLRVLDLSNNKMHFI 524

  Fly   277 GDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQSLTELILSDNKL----------LNEIDEEAL 331
            ..:.|..|:.|..|.::| :.|:.:....|:.|::||:|.|.:|||          |..::|..|
Zfish   525 LPDAFNDLSALKDLDLSF-NFLHNLPEDIFASLRNLTKLHLQNNKLRYLPSRLFSALVGLEELHL 588

  Fly   332 SKN----VTGGQYLDYPPLEKVYLNNCNVSTLPKELLVRWDKLKALDLRFNPWNCDE------SN 386
            .:|    :...|:.....|.::.:.:..:.::....|:...|||.:.|..|||:|..      |.
Zfish   589 DRNYIQRIHPTQFEGLVKLHELDMKSNQLRSMEDGTLMPLRKLKRIHLDGNPWDCSTVVILYISQ 653

  Fly   387 DFLINVLIDRINKTTPVLAKDVKCGGP 413
            .|..|.   ::.||||:.:.......|
Zfish   654 WFNNNT---QLVKTTPMCSSGQNLSNP 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	106/423 (25%)
		leucine-rich repeat	85..104	CDD:275380	9/29 (31%)
		LRR_8	105..174	CDD:290566	26/68 (38%)
		leucine-rich repeat	105..128	CDD:275380	9/22 (41%)
		leucine-rich repeat	129..163	CDD:275380	12/33 (36%)
		LRR_8	163..222	CDD:290566	26/79 (33%)
		leucine-rich repeat	164..187	CDD:275380	9/22 (41%)
		leucine-rich repeat	188..214	CDD:275380	12/38 (32%)
		leucine-rich repeat	215..238	CDD:275380	7/23 (30%)
		leucine-rich repeat	239..261	CDD:275380	6/43 (14%)
		LRR_8	260..322	CDD:290566	23/84 (27%)
		leucine-rich repeat	262..286	CDD:275380	11/46 (24%)
		leucine-rich repeat	287..311	CDD:275380	6/23 (26%)
		leucine-rich repeat	346..369	CDD:275380	2/22 (9%)
		leucine-rich repeat	370..388	CDD:275380	8/23 (35%)
si:dkey-182i3.11	XP_021322095.1	PLN00113	97..>617	CDD:331614	104/417 (25%)
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..176	CDD:275380
		leucine-rich repeat	177..200	CDD:275380
		leucine-rich repeat	201..224	CDD:275380	3/9 (33%)
		leucine-rich repeat	225..248	CDD:275380	4/22 (18%)
		leucine-rich repeat	249..272	CDD:275380	2/22 (9%)
		leucine-rich repeat	273..296	CDD:275380	7/25 (28%)
		leucine-rich repeat	297..320	CDD:275380	9/22 (41%)
		leucine-rich repeat	321..344	CDD:275380	12/33 (36%)
		leucine-rich repeat	345..368	CDD:275380	9/22 (41%)
		leucine-rich repeat	369..392	CDD:275380	7/22 (32%)
		leucine-rich repeat	393..438	CDD:275380	13/44 (30%)
		leucine-rich repeat	417..436	CDD:275380	6/18 (33%)
		leucine-rich repeat	439..462	CDD:275380	3/22 (14%)
		leucine-rich repeat	463..486	CDD:275380	3/22 (14%)
		leucine-rich repeat	487..510	CDD:275380	8/22 (36%)
		leucine-rich repeat	511..534	CDD:275380	3/22 (14%)
		leucine-rich repeat	535..558	CDD:275380	6/23 (26%)
		leucine-rich repeat	559..582	CDD:275380	8/22 (36%)
		leucine-rich repeat	583..606	CDD:275380	4/22 (18%)
		leucine-rich repeat	607..628	CDD:275380	2/20 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910