DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5096 and lrrn1-like

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001106456.1	Gene:	lrrn1-like / 100127637	XenbaseID:	XB-GENE-492890	Length:	738	Species:	Xenopus tropicalis

Alignment Length:	408	Identity:	110/408 - (26%)
Similarity:	178/408 - (43%)	Gaps:	69/408 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LAAAIFCIVLSQVSGQTKD--------ETTTTETPK---EKIKVIDSKLCKKCN----CYIDTNL 58
            :...:|.|||..|...|..        ||....||:   .:.|.:|      ||    .:|..||
Frog    18 METCLFVIVLHSVFFSTLGVCPPQCVCETRPWFTPQSVYHEAKTVD------CNDLLLTHIPENL 76

  Fly    59 LDCSEKLQ------DWLSAEDWE--DLTNGNVVFKTINLEHNNLTSVPILPKYDVEN------LY 109
               |..:|      :.:|...||  :|:|    ...::|..|:..|:..|   .|.|      ||
Frog    77 ---STDIQVLLLQSNKISHLTWELQELSN----LTELDLSQNHFQSIDDL---GVSNLSQLITLY 131

  Fly   110 LANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDL 174
            |..||:..:...:.::|..|..|.::||:::        :.||   :.|..|..|..|:|..|.|
Frog   132 LEENQLRELPDYSLKDLGSLEELYINHNQIS--------YIGP---RAFSGLGRLLRLHLNANRL 185

  Fly   175 HSLDADLFEHIPHIEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGPRDL 239
            ..:|...||.:|::|.|::..|....:..|:...:..|.||.:   :.||::.:|:....|...|
Frog   186 EIIDPRWFEDLPNLEILMVGENPVTALQSLNFQPLGRLHSLVL---AGMELEHIPENAFQGLDYL 247

  Fly   240 EIFIAAGNLFNQLPK-ALKYATNLTSLVLNENPIENLIGDNVFPPLTKLTHLSMTFMSKLYKIGP 303
            |......|...::|| |||....|..|.||:|||..:.|.: |..:..|..||:..|.:|.::..
Frog   248 ESLSFFDNRLTEVPKEALKNLKLLKFLDLNKNPIPEIRGGD-FTGMEHLEELSLNSMEELERVEA 311

  Fly   304 GAFSELQSLTELILSDNKLLNEIDEEALSKNVTGGQYLDYPPLEKVYLNNCNVSTLPKELLVRWD 368
            .||.:|..|.:|.:.:|..|:.:|.||.|.|:..        |:.:.|||..::.:|.::.....
Frog   312 EAFQDLPELIKLEMCNNPRLSYLDPEAFSSNLGA--------LKTLLLNNNRLAMVPLKIFQALP 368

  Fly   369 KLKALDLRFNPWNCDESN 386
            .|..:.|..||..||..|
Frog   369 GLLEISLYSNPIRCDCQN 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	86/317 (27%)
		leucine-rich repeat	85..104	CDD:275380	4/18 (22%)
		LRR_8	105..174	CDD:290566	20/74 (27%)
		leucine-rich repeat	105..128	CDD:275380	8/28 (29%)
		leucine-rich repeat	129..163	CDD:275380	8/33 (24%)
		LRR_8	163..222	CDD:290566	16/58 (28%)
		leucine-rich repeat	164..187	CDD:275380	8/22 (36%)
		leucine-rich repeat	188..214	CDD:275380	5/25 (20%)
		leucine-rich repeat	215..238	CDD:275380	5/22 (23%)
		leucine-rich repeat	239..261	CDD:275380	8/22 (36%)
		LRR_8	260..322	CDD:290566	20/61 (33%)
		leucine-rich repeat	262..286	CDD:275380	9/23 (39%)
		leucine-rich repeat	287..311	CDD:275380	8/23 (35%)
		leucine-rich repeat	346..369	CDD:275380	5/22 (23%)
		leucine-rich repeat	370..388	CDD:275380	7/17 (41%)
lrrn1-like	NP_001106456.1	NEL	<52..>262	CDD:330839	58/239 (24%)
		leucine-rich repeat	60..79	CDD:275380	8/27 (30%)
		leucine-rich repeat	80..102	CDD:275380	5/21 (24%)
		LRR_8	101..161	CDD:316378	17/66 (26%)
		leucine-rich repeat	103..126	CDD:275380	6/25 (24%)
		leucine-rich repeat	127..150	CDD:275380	6/22 (27%)
		leucine-rich repeat	151..174	CDD:275380	8/33 (24%)
		leucine-rich repeat	175..198	CDD:275380	8/22 (36%)
		leucine-rich repeat	199..222	CDD:275380	4/22 (18%)
		leucine-rich repeat	223..246	CDD:275380	7/25 (28%)
		leucine-rich repeat	247..294	CDD:275380	17/47 (36%)
		LRR_8	294..356	CDD:316378	21/69 (30%)
		leucine-rich repeat	295..319	CDD:275380	8/23 (35%)
		leucine-rich repeat	320..345	CDD:275380	9/24 (38%)
		leucine-rich repeat	346..367	CDD:275380	5/20 (25%)
		PCC	351..>412	CDD:188093	11/36 (31%)
		leucine-rich repeat	370..382	CDD:275378	4/11 (36%)
		Ig	448..515	CDD:319273
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910