Protein Alignment gny and ALG6

DIOPT Version :9

• Sequence 1: NP_001260338.1
• Gene: gny / 34409
• FlyBaseID: FBgn0032234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_014644.1
• Gene: ALG6 / 854163
• SGDID: S000005528
• Length: 544
• Species: Saccharomyces cerevisiae
• Alignment Length: 499
• Identity: 190/499 - (38%)
• Similarity: 279/499 - (55%)
• Gaps: 52/499 - (10%)

  Fly    15 VRSIISLYSYSGFDSPPMHGDYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTAYHSY 79
            :|..|.|..|||..|||::||:||||||.|||.:|.:.:||.    .||||||||||||||:|||
Yeast    49 LRCTIGLGPYSGKGSPPLYGDFEAQRHWMEITQHLPLSKWYW----YDLQYWGLDYPPLTAFHSY 109

  Fly    80 LVGRIGASIDPRFVELHKSRGFESKEH--KRFMRATVVSADVLIYLPAMLLLAYSLDKAFRSDDK 142
            |:|.||:..:|.:..|.|||||||.::  |.:||:||:.:|:|.|.||::.....|.: :|:...
Yeast   110 LLGLIGSFFNPSWFALEKSRGFESPDNGLKTYMRSTVIISDILFYFPAVIYFTKWLGR-YRNQSP 173

  Fly   143 L---FLFTLVAAYPGQTLIDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELY 204
            :   ...:.:...|...|||:||||||::.||..|.||..:|...:..||..|.|::.:|||.||
Yeast   174 IGQSIAASAILFQPSLMLIDHGHFQYNSVMLGLTAYAINNLLDEYYAMAAVCFVLSICFKQMALY 238

  Fly   205 HSLPFFAFLLGECVSQKSFASF-IAEISRIAAVVLGTFAILWVPWL---GSLQAVLQVLHRLFPV 265
            ::..|||:||...:   .|..| ||.::.||...|.||||::.|..   |.|:.:.|.:||:||.
Yeast   239 YAPIFFAYLLSRSL---LFPKFNIARLTVIAFATLATFAIIFAPLYFLGGGLKNIHQCIHRIFPF 300

  Fly   266 ARGVFEDKVANVWCAVNVVWKLKKHISNDQMALVCIACTLIASLPTNV--LLFRRRTNVGFLLAL 328
            |||:|||||||.||..||..|.|:..:..|:.|..:..|:|..||..:  ||..::..:.::  |
Yeast   301 ARGIFEDKVANFWCVTNVFVKYKERFTIQQLQLYSLIATVIGFLPAMIMTLLHPKKHLLPYV--L 363

  Fly   329 FNTSLAFFLFSFQVHEKTILLTALPALFLLKCWPDEMILFL-----EVTVFSMLPLLARDELLVP 388
            ...|::||||||||||||||:..|| :.||....|..:|.|     .|.:|::.|||.:|.|.:.
Yeast   364 IACSMSFFLFSFQVHEKTILIPLLP-ITLLYSSTDWNVLSLVSWINNVALFTLWPLLKKDGLHLQ 427

  Fly   389 AVVATVAFHLIFKCFD---------------SKSKLSNEYPLKYIANISQI---LMISVVVA--- 432
            ..|:.:..:.:...|.               |.|.::::|..:.:...:.:   .:|...:|
Yeast   428 YAVSFLLSNWLIGNFSFITPRFLPKSLTPGPSISSINSDYRRRSLLPYNVVWKSFIIGTYIAMGF 492

  Fly   433 ----SLTVPAPTKYPDLWPLIISVTSCGHFFLFFLWGNVQQFSS 472
                ...|..|:||||||.|:........|.:|:||...:.|:|
Yeast   493 YHFLDQFVAPPSKYPDLWVLLNCAVGFICFSIFWLWSYYKIFTS 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gny	NP_001260338.1	Alg6_Alg8	30..463	CDD:281190	179/473 (38%)
ALG6	NP_014644.1	Alg6_Alg8	64..528	CDD:281190	179/474 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343935
Domainoid	1	1.000	295	1.000	Domainoid score	I226
eggNOG	1	0.900	-	-		E1_KOG2575
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6920
Inparanoid	1	1.050	297	1.000	Inparanoid score	I510
Isobase	1	0.950	-	0.741681	Normalized mean entropy	S1324
OMA	1	1.010	-	-		QHG55006
OrthoFinder	1	1.000	-	-		FOG0005142
OrthoInspector	1	1.000	-	-		oto100260
orthoMCL	1	0.900	-	-		OOG6_102923
Panther	1	1.100	-	-	LDO	PTHR12413
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R44
SonicParanoid	1	1.000	-	-		X3661
TreeFam	1	0.960	-	-
	16	15.740