Protein Alignment gny and ALG6

DIOPT Version :9

• Sequence 1: NP_001260338.1
• Gene: gny / 34409
• FlyBaseID: FBgn0032234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_037471.2
• Gene: ALG6 / 29929
• HGNCID: 23157
• Length: 507
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 216/489 - (44%)
• Similarity: 298/489 - (60%)
• Gaps: 42/489 - (8%)

  Fly    11 LGLAVRSIISLYSYSGFDSPPMHGDYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTA 75
            :||.||..:||.||||...|||.|||||||||||||.||.|.:||.|||:|:|||||||||||||
Human    13 IGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTA 77

  Fly    76 YHSYLVGRIGASIDPRFVELHKSRGFESKEHKRFMRATVVSADVLIYLPAMLLLAYSLDKAFRSD 140
            |||.|...:...|:|.::.||.|||:||:.||.|||.||:.||:|||:||::|....| |...:.
Human    78 YHSLLCAYVAKFINPDWIALHTSRGYESQAHKLFMRTTVLIADLLIYIPAVVLYCCCL-KEISTK 141

  Fly   141 DKLFLFTLVAAYPGQTLIDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELYH 205
            .|:.....:..|||..|||.||||||::|||||...:..|........:..|.||:|||||||||
Human   142 KKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYH 206

  Fly   206 SLPFFAFLLGECVSQ----KSFASFIAEISRIAAVVLGTFAILWVPWLGSLQAVLQVLHRLFPVA 266
            :||||.||||:|..:    |.|...:    ::|.:|:.:|.:.|:|:....:..||||.|||||.
Human   207 ALPFFCFLLGKCFKKGLKGKGFVLLV----KLACIVVASFVLCWLPFFTEREQTLQVLRRLFPVD 267

  Fly   267 RGVFEDKVANVWCAVNVVWKLKKHISNDQMALVCIACTLIASLPTNVLLFRRRTNVGFLLALFNT 331
            ||:|||||||:||:.||..|:|..:......::....|.::.||..:.|..:.::.||...|.:.
Human   268 RGLFEDKVANIWCSFNVFLKIKDILPRHIQLIMSFCSTFLSLLPACIKLILQPSSKGFKFTLVSC 332

  Fly   332 SLAFFLFSFQVHEKTILLTALPALFLLKCWPDEMILFLEVTVFSMLPLLARDELLVPAVVATVAF 396
            :|:|||||||||||:|||.:||...:|...|.....||.|:.|||||||.:||||:|:||.|:||
Human   333 ALSFFLFSFQVHEKSILLVSLPVCLVLSEIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAF 397

  Fly   397 HL-------IFK---------------------CFDSKSKLSNEYPLKYIANISQILMISVVVAS 433
            .:       ||:                     ||...|::     ::|:..||.|.|:.:.:.:
Human   398 FIACVTSFSIFEKTSEEELQLKSFSISVRKYLPCFTFLSRI-----IQYLFLISVITMVLLTLMT 457

  Fly   434 LTVPAPTKYPDLWPLIISVTSCGHFFLFFLWGNV 467
            :|:..|.|.|||:.:::...||.:|..|.::.|:
Human   458 VTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gny	NP_001260338.1	Alg6_Alg8	30..463	CDD:281190	205/464 (44%)
ALG6	NP_037471.2	Alg6_Alg8	32..485	CDD:308661	204/462 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147607
Domainoid	1	1.000	394	1.000	Domainoid score	I769
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6920
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1937
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55006
OrthoDB	1	1.010	-	-		D379099at33208
OrthoFinder	1	1.000	-	-		FOG0005142
OrthoInspector	1	1.000	-	-		oto91502
orthoMCL	1	0.900	-	-		OOG6_102923
Panther	1	1.100	-	-	LDO	PTHR12413
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R44
SonicParanoid	1	1.000	-	-		X3661
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.940