DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and CD86

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_787058.5	Gene:	CD86 / 942	HGNCID:	1705	Length:	329	Species:	Homo sapiens

Alignment Length:	180	Identity:	41/180 - (22%)
Similarity:	70/180 - (38%)	Gaps:	38/180 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEPKRWHLHLSCFLLLLSSTFSDVGKITSSQNHFGNT--LQSQFNTKNNTRVIAQKGGLAILPCV 63
            |:| :..:.||..|.:::...|....: ..|.:|..|  |..||....|..:
Human     1 MDP-QCTMGLSNILFVMAFLLSGAAPL-KIQAYFNETADLPCQFANSQNQSL------------- 50

  Fly    64 VKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGH-------WSLRIKAVREEDRGF 121
                |...|.|..:::..|..|.|.....|.    .|:::||.       |:||:..::.:|:|.
Human    51 ----SELVVFWQDQENLVLNEVYLGKEKFDS----VHSKYMGRTSFDSDSWTLRLHNLQIKDKGL 107

  Fly   122 YECQL-SIYPTQSIVI-----ELKIVEAVAEISSAPELHIDETSTLRLEC 165
            |:|.: ...||..|.|     ||.::...::....|..:|.|...:.|.|
Human   108 YQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTC 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	17/84 (20%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	16/76 (21%)
CD86	NP_787058.5	IgV_CD86	28..133	CDD:319336	30/125 (24%)
CD86	NP_787058.5	Ig	136..221	CDD:325142	5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I12529
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1051626at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920