DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	341	Identity:	78/341 - (22%)
Similarity:	117/341 - (34%)	Gaps:	133/341 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 VIAQKGGLAILPCVVKVNSPA------TVSWIRRKDFQL---LTVGLSTHSSDKRFLVEHTRHMG 105
            |:.:.|..|:|.|  .:..||      .:.|: |..|.|   :..||.:...|..: |...|...
Mouse    29 VVGRAGESAVLGC--DLLPPAGHPPLHVIEWL-RFGFLLPIFIQFGLYSPRIDPDY-VGRVRLQT 89

  Fly   106 HWSLRIKAVREEDRGFYECQL--------------------------SIYPTQSIVIELKIVEAV 144
            ..||:|:.:|.||:|:|||::                          ....|..:|:|:|.:|||
Mouse    90 GASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAV 154

  Fly   145 AEISSAPELHIDETSTLRLECKLKRATENPAFVFWYHDSKMINYDSQGGFVVTSIGQSNPQSGQF 209
                           |||  | :.|.:..| :|.|    |....|...|     .||...|:|..
Mouse   155 ---------------TLR--C-VARGSPQP-YVTW----KFRGQDLGKG-----QGQVQVQNGTL 191

  Fly   210 Y----------------RSSPANKSRAT---------MPMESSNGVLNSLLGSSDAIKAPAANVP 249
            :                .||..:.:.||         :.:..||..:||....|.|.:|.|  .|
Mouse   192 WIRRVERGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEA--YP 254

  Fly   250 SSTPYMTQQHQSAYLLNPSVSVLTVKQVNFR-----------------HAGNYTCAPSNA----- 292
            ::..|...|        ..|:|..:.::..|                 .||:|||.|||.
Mouse   255 ANLTYSWFQ--------DGVNVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLHPP 311

  Fly   293 ---------RPASITV 299
                     .||.:||
Mouse   312 SASAYLTVLYPAQVTV 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	26/111 (23%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	24/78 (31%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	26/84 (31%)
		Ig	136..223	CDD:386229	26/114 (23%)
		Ig_3	227..305	CDD:372822	20/87 (23%)
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900