DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	345	Identity:	83/345 - (24%)
Similarity:	128/345 - (37%)	Gaps:	92/345 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLSSTFSDVGKITSSQNHFGNTLQSQFNTKNNTRVIAQKGGLAILPC--VVKVN-SPATVSWIRR 77
            |::|.||..|  |::|...|...:.||       |.::.|...||.|  |..:| .|..|.|.:
Zfish     8 LIASVFSTRG--TAAQGAHGVREEPQF-------VTSRAGETVILGCDVVHPLNGQPYVVEWFK- 62

  Fly    78 KDFQL-----LTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIYPTQSIVIE 137
              |.:     :.........|..:....:.| |..||||:.||.||:|:|||::       :::|
Zfish    63 --FGVPIPFFINFRFYPPHVDPEYAGRASLH-GKSSLRIERVRSEDQGWYECKV-------LMLE 117

  Fly   138 LK------------IVEAVAEISSAPELHID--ETSTLRLECKLKRATENP-AFVFWYHDSKMIN 187
            .:            .|.|....:..|..:::  |..::.|.|   .|..|| ..|.|..:...:.
Zfish   118 QQYHTFHNGSWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSC---TAFGNPKPSVSWLREGNPVQ 179

  Fly   188 YD-----SQGGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGVLNSLLGSSDAIKAPAAN 247
            ..     |.|...:.||.:.:         ..|...||......:......|:.....|.:|..|
Zfish   180 DSTKYKVSDGSLTLVSISRED---------RGAYTCRAYSEQGEAVHTTRLLVQGPPFIVSPPEN 235

  Fly   248 VP---SSTPYMTQQHQS-----AYL-------------LNPSVSV-----LTVKQVNFRHAGNYT 286
            :.   |...:.|.|.::     .|.             |...||:     |.:.||....||.||
Zfish   236 ITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPEDAGKYT 300

  Fly   287 CAPSNA--RPAS----ITVH 300
            |:|||:  ||.|    :|||
Zfish   301 CSPSNSLGRPPSASAYLTVH 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	26/84 (31%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	24/77 (31%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	28/93 (30%)
		Ig	41..113	CDD:143165	24/75 (32%)
		IG_like	144..223	CDD:214653	15/90 (17%)
		IGc2	151..208	CDD:197706	13/68 (19%)
		I-set	227..319	CDD:254352	24/91 (26%)
		Ig	<263..319	CDD:299845	17/55 (31%)
		Ig_2	326..414	CDD:290606
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910