DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and igsf9ba

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	365	Identity:	77/365 - (21%)
Similarity:	138/365 - (37%)	Gaps:	88/365 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EPKRWHLHLSCFLLLLSSTFSDVGKITSSQNHFGNTLQSQFN---TKNNT---RVIAQKGGLAIL 60
            |.:.|:   .|.:|:|...:...        |.|:.:....|   |.::|   .|.|::||...|
Zfish   106 EDQGWY---ECRVLMLEQQYDTF--------HNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITL 159

  Fly    61 PCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQ 125
            .|....|....|:|:|..| ||        :|.:::.|      ...||.::|:..||||.|.|:
Zfish   160 TCTAFGNPKPVVTWLREGD-QL--------TSTRKYTV------SDGSLTVQAITREDRGAYSCR 209

  Fly   126 LSIYPTQSIVIELKIVEAVAEISSAPE-LHIDETSTLRLECKLKRATENPAFV-FWYHDSKMINY 188
            ......:::.....:|:....|.:.|| :.::.:...:..|:.:....|..:. :|..|:.....
Zfish   210 AHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKN 274

  Fly   189 DSQ--------GGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGVLNSLLGSSDAIKAPA 245
            |.:        |..::..:   .|:....|..||:|.                 ||.|
Zfish   275 DLKLRVRIFIDGTLIIYRV---KPEDAGKYTCSPSNS-----------------LGIS------- 312

  Fly   246 ANVPSSTPYMTQQHQSAYLLNPSVSVLTVKQVNFRHAGNYTCAPSNARPASITV------HVLRG 304
               ||::.|:|.|:.:..:..|.|..:..|.     :|...| |.:|.|...:|      :.||.
Zfish   313 ---PSASAYLTVQYPARVVNMPPVIYVPRKL-----SGIIRC-PVDANPPVTSVRWEKDGYPLRI 368

  Fly   305 EK---TAAMQHANRSILDTETNGNGTFGLITLGGLNGTSG 341
            ||   .:.|...:..:.:...:..||:..:....| ||.|
Zfish   369 EKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVL-GTMG 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	24/76 (32%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	21/69 (30%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	3/11 (27%)
		I-set	139..225	CDD:254352	26/100 (26%)
		I-set	229..321	CDD:333254	20/121 (17%)
		Ig	345..415	CDD:325142	16/65 (25%)
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810