DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and paplna

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	283	Identity:	65/283 - (22%)
Similarity:	121/283 - (42%)	Gaps:	56/283 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EPKRWHLHLSCFLLLLSSTFSDVG--KITSSQNHFGNTLQSQFNTKNNTRVIAQKGGLAILPC-V 63
            :.||.|.::  :|.:..|:.::.|  ::.|||::...: .|:||...:..|.|:.|..|.|.| |
Zfish   908 DDKRDHRYI--YLSVSGSSQNNAGISEVDSSQSYTSQS-SSRFNIDYSPLVEARAGQTAKLQCSV 969

  Fly    64 VKVNS--PATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQL 126
            :.|::  ..|:.|.|        .|...:|      :.|::| ...:|.||.:..:|.|.|.|.:
Zfish   970 LPVSAIHAVTIHWSR--------AGQPLNS------LRHSQH-SDGTLVIKQLTADDSGLYTCTV 1019

  Fly   127 S-IYPTQSIVIELKIVEAVAEISSAP-ELHIDETSTLRLECKLKRATENPAFVFWYH-------D 182
            : ....:...::|:::..: .|:.|| ::.:.:.||.:|.|.:.....|   |.|..       |
Zfish  1020 TDAQKFEERQVQLRVLGDL-RITKAPIDVDVVQGSTAQLACVVTGENVN---VGWSRNGVPVRPD 1080

  Fly   183 SKMINYDSQGGFVVTSIGQS--------NPQSGQFYRSSPANKSRATMPMESSNGVLNSLLGSSD 239
            ...::..:.|..::.:: ||        |..:|....|:.|....|..|.:..:|   ....|||
Zfish  1081 GHRVHVSADGTLILNNV-QSVDEGTYTCNAYTGTLSVSAAAEIRLAKTPQQDIDG---GQFSSSD 1141

  Fly   240 AIKAP-AANVP-------SSTPY 254
            .:..| .||..       .|:||
Zfish  1142 CVDQPELANCKLIVYARLCSSPY 1164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	22/79 (28%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	19/72 (26%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706	20/76 (26%)
		I-set	1039..1121	CDD:333254	17/85 (20%)
		PLAC	1142..1173	CDD:312271	6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900