DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and lrit3a

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001122166.1	Gene:	lrit3a / 558559	ZFINID:	ZDB-GENE-080723-63	Length:	636	Species:	Danio rerio

Alignment Length:	174	Identity:	43/174 - (24%)
Similarity:	72/174 - (41%)	Gaps:	37/174 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 PELHIDETSTLRLECKLKRATENPAFVFWYHD---SKMINYDSQGGFVVTSIGQ----SNPQ--S 206
            |..:..:.:.|.|:       :||    ||.|   ||:|......|..|..:.|    |.|:  |
Zfish   184 PSANTSQKTVLGLQ-------DNP----WYCDCRISKLIELSKMAGIPVVLMDQVLTCSGPEHLS 237

  Fly   207 GQFYRSSPANKSRATMPMESSNGVLNSLLGSSDAIKAPAANVPSSTPYMTQQHQSAYLLNPSV-- 269
            |..::.:..::......|.|:..: .|.|||:..::..|...|:.|...|....|  ::|.:|
Zfish   238 GVLFQRAELDQCVKPTVMTSATKI-TSPLGSNVLLRCDANGFPTPTLLWTTADGS--VVNNTVVQ 299

  Fly   270 ---------SVLTVKQVNFRHAGNYTCAPSNA---RPASITVHV 301
                     |:|::..:.|:.||:|.|...|.   ..|.||:.|
Zfish   300 ESPGEGVRWSILSLHSIVFKDAGDYRCKAKNVAGNAEAYITLSV 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706
lrit3a	NP_001122166.1	LRR_8	81..141	CDD:290566
		leucine-rich repeat	83..106	CDD:275378
		LRR_4	107..145	CDD:289563
		leucine-rich repeat	107..130	CDD:275378
		LRR_8	129..>171	CDD:290566
		LRR_4	129..170	CDD:289563
		leucine-rich repeat	131..154	CDD:275378
		leucine-rich repeat	155..168	CDD:275378
		TPKR_C2	199..249	CDD:301599	15/53 (28%)
		Ig	252..343	CDD:299845	24/93 (26%)
		IG_like	261..343	CDD:214653	22/84 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900