DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr19 and NCAM2

DIOPT Version :9

Sequence 1:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster
Sequence 2:XP_011527877.1 Gene:NCAM2 / 4685 HGNCID:7657 Length:874 Species:Homo sapiens


Alignment Length:351 Identity:69/351 - (19%)
Similarity:126/351 - (35%) Gaps:78/351 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 VNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLV--EHTRHMGHWSLRIKAVREEDRGFYECQLSI 128
            :..|.::.|...:..:::        |.:|.:|  |..|.    .|.|.....||.|.|.||.:.
Human    70 IGEPESIDWYNPQGEKII--------STQRVVVQKEGVRS----RLTIYNANIEDAGIYRCQATD 122

  Fly   129 Y--PTQSIVIELKIVEAVA--EISSAPELHIDETSTLRLECKLKRATENPA-FVFWYHDSKMINY 188
            .  .||...:.|:|.:.:.  |:.|..|....|.:  .:.|   |.:.:|| .|.|.:.::.:..
Human   123 AKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDA--EVVC---RVSSSPAPAVSWLYHNEEVTT 182

  Fly   189 DSQGGFVVTS-----IGQSNPQSGQFYRSSPANKSRA-----------------TMPMESSNGVL 231
            .|...|.:.:     |...|......||.....::|.                 :||.:|.|...
Human   183 ISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATA 247

  Fly   232 NSLLGSSDAIKAPAANVPSSTPYMTQ---QHQSAYLLNPSVSVLTVKQVNFRHAGNYTCAPSN-- 291
            ......:.:.:|..:..|:.:.:...   :....|:|..|.:.|||:.:.....|.|.|..:|  
Human   248 ERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKA 312

  Fly   292 ---ARPASITV----HVLR---------GEKTAAMQHANRSILD----------TETNGNGTF-G 329
               .:.|.:.|    |:::         |:.|.........|.:          |.|.|:.:. |
Human   313 GEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDG 377

  Fly   330 LITLGGLNGTSGVTLAGGILYFSGLF 355
            .|.:.|.:|:|.:.:....|..||.:
Human   378 RIEVKGQHGSSSLHIKDVKLSDSGRY 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 15/62 (24%)
IGc2 55..125 CDD:197706 13/60 (22%)
NCAM2XP_011527877.1 Ig1_NCAM-2 46..137 CDD:143274 18/78 (23%)
I-set 47..136 CDD:254352 18/77 (23%)
I-set 142..218 CDD:254352 16/80 (20%)
IGc2 153..214 CDD:197706 13/65 (20%)
Ig 233..326 CDD:299845 18/92 (20%)
I-set 240..323 CDD:254352 15/82 (18%)
Ig5_NCAM-2 325..422 CDD:143278 15/79 (19%)
IG_like 333..420 CDD:214653 14/71 (20%)
IG_like 438..515 CDD:214653
IGc2 439..507 CDD:197706
FN3 521..613 CDD:238020
fn3 619..703 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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