DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and opcml

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	304	Identity:	72/304 - (23%)
Similarity:	126/304 - (41%)	Gaps:	51/304 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSL 109
            |:|  :..::|..|:|.|.:. |..:.|:|:.|.  .:|..|....|.|.|.::.:|. :..:|:
Zfish    39 KDN--ITVRQGDSAVLKCSMD-NKVSRVAWLNRT--TILFTGNEKWSLDPRVVLLNTA-VNEYSI 97

  Fly   110 RIKAVREEDRGFYECQ-LSIYPTQSIVIELKIVEAVAEI-SSAPELHIDETSTLRLECKLKRATE 172
            :|..|...|.|.|.|. |:....:|..:.| ||:..|.| :.:.::.::|.|.:.|.| |.....
Zfish    98 KILNVNLYDEGPYVCSILTNKKPESTKVHL-IVQVPARIVNVSTDVSVNEGSNVSLMC-LAIGRP 160

  Fly   173 NPAFVFWYHDSKMINYDSQGGFV---------------VTSIGQSNP--QSGQFYRSSPANKSRA 220
            .|:.::.:..||.....::|.:|               :||...|.|  ::.|...:.|...|||
Zfish   161 EPSILWKFRSSKGNRIVTEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTVNYPPVISRA 225

  Fly   221 TMPMESSNGVLNSLLGSSDAIKAPAANVP-SSTPYMTQQHQSAYLLN----------PSVSVLTV 274
                 .|.|   :.:|....:...|:.|| :...:...:.:   :||          ...|:||.
Zfish   226 -----RSTG---TAVGQKGVLWCEASAVPLADFQWFKGERR---ILNGFNGVKIENKGKQSMLTF 279

  Fly   275 KQVNFRHAGNYTCAPSNARPASITVHVLRGEKTAAMQHANRSIL 318
            ..|:....|||||...|....:....:|.|  ..|:...|.:.|
Zfish   280 FNVSEEDYGNYTCVAINTLGITNASIILYG--PGAIHDVNNAAL 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	21/77 (27%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	20/69 (29%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	25/94 (27%)
		IG_like	41..129	CDD:214653	25/94 (27%)
		IG_like	139..216	CDD:214653	15/77 (19%)
		IGc2	146..202	CDD:197706	11/56 (20%)
		I-set	219..307	CDD:254352	22/98 (22%)
		ig	223..307	CDD:278476	21/94 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810