DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and klg

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	70/342 - (20%)
Similarity:	132/342 - (38%)	Gaps:	53/342 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 W--HLHLSCFLLLLSSTFSDVGKITSSQNHFGNTLQS------------QFNTKNNT-RVIAQKG 55
            |  |.|.......:.:..|:.|   |:.....|..||            :|.::.:| |.:.  |
  Fly    56 WLLHAHAGSGGFAVEAAISNRG---SNSRSMSNVQQSAVAASTLTATLPRFLSRGHTYRAVV--G 115

  Fly    56 GLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRG 120
            ...:|||.|:......:.|  |:...:||......:.|:|     .|.:..::|.|..:..:|.|
  Fly   116 DTLVLPCQVENLGNFVLLW--RRGTNVLTASNIMVTRDER-----VRLIDGYNLEISDLEPQDAG 173

  Fly   121 FYECQLS--IYPTQSIVIELKIVEAVAEISSAPELHIDETSTLRLECKLKRATENPA-FVFWYHD 182
            .|.||:|  |...|...:|:.:..:|..|.::.:|...:...:.||||   .:.||. .::|...
  Fly   174 DYVCQISDKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLECK---GSGNPVPSIYWTKK 235

  Fly   183 SKMINYDSQ-GGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGVL--------NSLLGSS 238
            |......:: |...:.::.:...|....|:.:..|.....:.::....||        .|.:.|.
  Fly   236 SGANKSTARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSG 300

  Fly   239 DAIKAPAANVPSSTPYMT-QQHQSAYLL----------NPSVSVLTVKQVNFRHAGNYTCAPSNA 292
            :..:|....:..:.|..| ..:|:::.:          ..:..:||::.:.....|||:|...|:
  Fly   301 EGFEAKLVCIVFADPVATVSWYQNSFPIQSTDRRIMATRANRHMLTIRHIQQEDFGNYSCVADNS 365

  Fly   293 RPASITVHVLRGEKTAA 309
            ...|.....|.|...||
  Fly   366 LGRSRKYMELSGRPGAA 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	19/76 (25%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	17/69 (25%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	13/65 (20%)
		IG_like	109..195	CDD:214653	25/94 (27%)
		Ig	118..191	CDD:143165	21/79 (27%)
		IG_like	205..274	CDD:214653	13/71 (18%)
		IGc2	213..273	CDD:197706	12/62 (19%)
		IGc2	301..367	CDD:197706	11/65 (17%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810