DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr19 and IGLON5

DIOPT Version :9

Sequence 1:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster
Sequence 2:NP_001094842.1 Gene:IGLON5 / 402665 HGNCID:34550 Length:336 Species:Homo sapiens


Alignment Length:296 Identity:73/296 - (24%)
Similarity:118/296 - (39%) Gaps:54/296 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 QFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRF-LVEHTRHM 104
            :||:..:...:.: |..|.|.|.:. .....|:|:.|.:  :|..|....:||.|. |:.:|.. 
Human    34 EFNSPADNYTVCE-GDNATLSCFID-EHVTRVAWLNRSN--ILYAGNDRWTSDPRVRLLINTPE- 93

  Fly   105 GHWSLRIKAVREEDRGFYECQLSI----YPTQSIVIELKIVEAVAEISSAPELHIDETSTLRLEC 165
             .:|:.|..|...|.|.|.|....    |.||..:| :.:...:..|||  .:.::|...:.|.|
Human    94 -EFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLI-VHVPARIVNISS--PVTVNEGGNVNLLC 154

  Fly   166 KLKRATENPAFVFW--YHDSKMINYDSQGGFVVTSIGQSNPQSGQF-------YRSSPANKSRAT 221
             |......|. |.|  ..|    .:.|:|..:..|..|.. |:|::       ..|:|  .||..
Human   155 -LAVGRPEPT-VTWRQLRD----GFTSEGEILEISDIQRG-QAGEYECVTHNGVNSAP--DSRRV 210

  Fly   222 M------PMESSNGVLNSLLGSSDAIKAPAANVPSSTPYMTQQHQSAYLLNPSV----------- 269
            :      |..:......:.||.:..::..|..||   |...|.::...||:...           
Human   211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVP---PADFQWYKDDRLLSSGTAEGLKVQTERT 272

  Fly   270 -SVLTVKQVNFRHAGNYTCAPSNARPA-SITVHVLR 303
             |:|....|:.||.|||||..:|...| |.::.:||
Human   273 RSMLLFANVSARHYGNYTCRAANRLGASSASMRLLR 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 21/77 (27%)
IGc2 55..125 CDD:197706 20/70 (29%)
IGLON5NP_001094842.1 Ig 41..129 CDD:416386 25/94 (27%)
Ig strand A' 41..46 CDD:409353 0/4 (0%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/4 (0%)
FR2 61..68 CDD:409353 2/6 (33%)
Ig strand C 61..67 CDD:409353 2/5 (40%)
CDR2 69..79 CDD:409353 2/11 (18%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 12/36 (33%)
Ig strand D 84..91 CDD:409353 2/6 (33%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 4/9 (44%)
FR4 122..129 CDD:409353 3/7 (43%)
Ig_3 134..199 CDD:404760 17/73 (23%)
Ig strand B 148..157 CDD:409353 3/9 (33%)
Ig strand C 162..170 CDD:409353 3/8 (38%)
Ig strand F 191..199 CDD:409353 1/7 (14%)
Ig strand G 202..212 CDD:409353 4/11 (36%)
Ig_3 217..295 CDD:404760 20/80 (25%)
putative Ig strand A 218..224 CDD:409353 1/5 (20%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 1/3 (33%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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