DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr19 and LRIT3

DIOPT Version :9

Sequence 1:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster
Sequence 2:NP_940908.3 Gene:LRIT3 / 345193 HGNCID:24783 Length:679 Species:Homo sapiens


Alignment Length:262 Identity:55/262 - (20%)
Similarity:98/262 - (37%) Gaps:56/262 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 NSPATVSWIRRKDFQLL-TVGLSTH--SSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSI 128
            ||.|...|....|..|| |:.|..:  :|.....:.:.:::.:..|....:......|.|....:
Human   115 NSLAAFPWASLLDMPLLRTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLESWTHL 179

  Fly   129 YPTQSIVIELKIVEAVAEISSAPELHIDETSTLRLECKLKRATENPAFVFWY---HDSKMINYDS 190
            ..|.|.|::|                    |..|:...|:   :||    |:   |.||||....
Human   180 VSTPSGVLDL--------------------SPSRIILGLQ---DNP----WFCDCHISKMIELSK 217

  Fly   191 QGGFVVTSIGQ----SNPQ--SGQFYRSSPANKSRATMPMESSNGVLNSLLGSSDAIKAPAANVP 249
            .....:..:..    |.|:  :|..::.:..........|.|:..:: |.|||:..::..|...|
Human   218 VVDPAIVLLDPLMTCSEPERLTGILFQRAELEHCLKPSVMTSATKIM-SALGSNVLLRCDATGFP 281

  Fly   250 SSTPYMTQQHQSAYLLNPSV-----------SVLTVKQVNFRHAGNYTCAPSN---ARPASITVH 300
              ||.:|.....:..:|.:|           |::::..::.:.||:|.|...|   ...|.:||.
Human   282 --TPQITWTRSDSSPVNYTVIQESPEEGVRWSIMSLTGISSKDAGDYKCKAKNLAGMSEAVVTVT 344

  Fly   301 VL 302
            ||
Human   345 VL 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 13/62 (21%)
IGc2 55..125 CDD:197706 13/60 (22%)
LRIT3NP_940908.3 LRR 1 56..79
leucine-rich repeat 59..82 CDD:275378
LRR_8 61..117 CDD:290566 1/1 (100%)
LRR 2 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3 104..128 4/12 (33%)
LRR_8 105..165 CDD:290566 11/49 (22%)
LRR_4 105..146 CDD:289563 10/30 (33%)
leucine-rich repeat 107..130 CDD:275378 5/14 (36%)
LRR 4 129..151 5/21 (24%)
LRR_4 131..170 CDD:289563 5/38 (13%)
leucine-rich repeat 131..154 CDD:275378 4/22 (18%)
LRR 5 152..175 2/22 (9%)
leucine-rich repeat 155..168 CDD:275378 1/12 (8%)
Ig 267..345 CDD:299845 19/79 (24%)
IG_like 267..345 CDD:214653 19/79 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 351..375
FN3 486..550 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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