DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr19 and Negr1

DIOPT Version :9

Sequence 1:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:267 Identity:66/267 - (24%)
Similarity:110/267 - (41%) Gaps:38/267 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 VIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAV 114
            ::.:||..|:|.|.:: :..:..:|:.|.  .::..|....|.|.|..:. |.:...:||:|:.|
Mouse    42 MLVRKGDTAVLRCYLE-DGASKGAWLNRS--SIIFAGGDKWSVDPRVSIS-TLNKRDYSLQIQNV 102

  Fly   115 REEDRGFYECQLSIY---PTQSIVIELKIVEAVAEISSAPELHIDETSTLRLECKLKRATENP-A 175
            ...|.|.|.|.:...   .|..:.:.:::...:.:||:  ::.|:|.:.:.|.|   .||..| .
Mouse   103 DVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISN--DMTINEGTNVTLTC---LATGKPEP 162

  Fly   176 FVFWYHDSKMINYDSQGGFVVTSIGQSNPQSGQFYRSSPAN--------KSR-----ATMPMESS 227
            .:.|.|.|.... ..:.|..:...|.:..|:|: |..|..|        |.|     |....|..
Mouse   163 VISWRHISPSAK-PFENGQYLDIYGITRDQAGE-YECSAENDVSFPDVKKVRVIVNFAPTIQEIK 225

  Fly   228 NGVLNSLLGSSDAIKAPAANVP-------SSTPYMTQQHQSAYLLNPSV-SVLTVKQVNFRHAGN 284
            :|.:..  |.|..|:...|.||       .....:....|...:.|.|. |:|||..|...|.||
Mouse   226 SGTVTP--GRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGN 288

  Fly   285 YTCAPSN 291
            |||..:|
Mouse   289 YTCVAAN 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 20/76 (26%)
IGc2 55..125 CDD:197706 18/69 (26%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 4/12 (33%)
Ig strand A' 40..46 CDD:409353 0/3 (0%)
IG_like 41..129 CDD:214653 21/90 (23%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/4 (0%)
FR2 61..68 CDD:409353 1/6 (17%)
Ig strand C 61..67 CDD:409353 1/5 (20%)
CDR2 69..79 CDD:409353 1/11 (9%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 12/35 (34%)
Ig strand D 84..91 CDD:409353 2/7 (29%)
Ig strand E 94..100 CDD:409353 2/5 (40%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig strand A' 139..144 CDD:409353 1/6 (17%)
IGc2 146..204 CDD:197706 16/62 (26%)
Ig strand B 150..157 CDD:409353 2/9 (22%)
Ig strand C 163..168 CDD:409353 1/4 (25%)
Ig strand C' 170..172 CDD:409353 1/1 (100%)
Ig strand E 180..186 CDD:409353 0/5 (0%)
Ig strand F 193..200 CDD:409353 3/7 (43%)
Ig_3 219..295 CDD:404760 22/77 (29%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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