DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr19 and Jaml

DIOPT Version :9

Sequence 1:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster
Sequence 2:XP_038938277.1 Gene:Jaml / 315610 RGDID:1562572 Length:379 Species:Rattus norvegicus


Alignment Length:367 Identity:72/367 - (19%)
Similarity:132/367 - (35%) Gaps:111/367 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 TKNNTRVIAQKGGLAILPCVVKVNSPA---TVSWIRRKD-----------FQLLTVGLSTHSSDK 94
            |.::.::....|..|::.|||:.....   .|.|:..|.           :..|:|......:..
  Rat    27 TVSSLKLRVHVGESALMGCVVQSTEEKPVDKVDWVFSKGEHAENEYVLYYYSSLSVPTGRFQNRS 91

  Fly    95 RFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIYPTQSIVIELKIVEAVAEISSAPELHIDETS 159
            |.:.:..|:.|  ||.::.|::.|.|.|.|::.:....|:..:..::..:.|  ...||.:....
  Rat    92 RLVGDLLRNDG--SLLLQDVQKADEGIYTCEIRLKNEGSVSKKFVLLHVLPE--EPKELRVHVGD 152

  Fly   160 TLRLECKLKRATENPAF--VFWYHDSK-------MINYDSQGGFVVTSIGQSNPQSGQF-----Y 210
            .:::.| ..|:||....  |.|...|.       :::||            .|..||.|     :
  Rat   153 PIQMGC-FFRSTEERRVTRVNWMFSSGKHAQEEIVLSYD------------FNMHSGTFQGQGRF 204

  Fly   211 RSSPANKSRATMPMESSNGVLNSLLGSSDAIKAPAANVPSSTPYMTQQHQSAYLLNPSVSVLTVK 275
            |    |:...|..:..::|                                      |:.:.|||
  Rat   205 R----NRVDLTGDISRNDG--------------------------------------SIMLQTVK 227

  Fly   276 QVNFRHAGNYTCAPSNARPAS---ITVHVLRGEKTAAMQHANRSI-LDTETNGNGTFGLITLGGL 336
            :.:   .|.|||:....:..|   |.:||::.|       :.||| ..|||.|.      ..|.|
  Rat   228 KSD---QGVYTCSIYLGKLESRKTIVLHVIQDE-------SPRSISTTTETAGK------QQGIL 276

  Fly   337 NGTSGVTLAG----GILYFSGLFLLMGAVVFDRFSLAATHKV 374
            :|...|.:.|    .:|....|.|::....:::.|:::...|
  Rat   277 DGNQLVIIVGIVCATLLLLPVLILIVKKTKWNKSSVSSIASV 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 20/90 (22%)
IGc2 55..125 CDD:197706 19/83 (23%)
JamlXP_038938277.1 V-set 33..139 CDD:400157 21/107 (20%)
FR2 58..69 CDD:409353 3/10 (30%)
CDR2 70..82 CDD:409353 1/11 (9%)
Ig strand C' 71..77 CDD:409353 0/5 (0%)
Ig strand C' 78..82 CDD:409353 1/3 (33%)
FR3 87..121 CDD:409353 10/35 (29%)
Ig strand D 90..96 CDD:409353 1/5 (20%)
Ig strand E 100..108 CDD:409353 3/9 (33%)
Ig strand F 115..122 CDD:409353 3/6 (50%)
V-set 141..253 CDD:400157 30/171 (18%)
Ig strand A' 144..150 CDD:409353 2/5 (40%)
Ig strand B 152..162 CDD:409353 1/10 (10%)
CDR1 162..169 CDD:409353 2/6 (33%)
Ig strand C 169..176 CDD:409353 2/6 (33%)
FR2 170..181 CDD:409353 3/10 (30%)
CDR2 182..196 CDD:409353 3/25 (12%)
Ig strand C' 183..189 CDD:409353 0/5 (0%)
Ig strand C' 191..196 CDD:409353 1/4 (25%)
FR3 204..238 CDD:409353 12/78 (15%)
Ig strand D 207..213 CDD:409353 1/5 (20%)
Ig strand E 217..225 CDD:409353 2/45 (4%)
Ig strand F 232..238 CDD:409353 4/5 (80%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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