DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr19 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	83/416 - (19%)
Similarity:	143/416 - (34%)	Gaps:	107/416 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EPKRWHLHLSCFLLLLSSTFSDVGKITSSQNHFGNTLQSQFN-----TKNNTRVI-AQKGGLAIL 60
            |.:.|:   .|.:|:|...:...        |.|:.:....|     |:...:.| |::||...:
  Rat   106 EDQGWY---ECKVLMLDQQYDTF--------HNGSWVHLTINAPPTFTETPPQYIEAKEGGSITM 159

  Fly    61 PCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQ 125
            .|....|....|:|:  |:..||:.......||             .||.:.:|..||||.|.|:
  Rat   160 TCTAFGNPKPIVTWL--KEGTLLSASGKYQVSD-------------GSLTVTSVSREDRGAYTCR 209

  Fly   126 LSIYPTQSIVIELKIVEAVAEISSAPE-LHIDETSTLRLECKLKRATENPAFVFWYHDSKMINYD 189
            ......:::.....:|:....|.|.|| :.::.:....|.|:.:....|..:. ||...:.:.:.
  Rat   210 AYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYT-WYWQDENVYFQ 273

  Fly   190 S----------QGGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGVLNSLLGSSDAIKAP 244
            :          .|..::..:   .|:....|...|:|.                 ||.|
  Rat   274 NDLKLRVRILIDGTLIIFRV---KPEDAGKYTCVPSNS-----------------LGRS------ 312

  Fly   245 AANVPSSTPYMTQQHQSAYLLNPSVSVLTVKQVNFRHAGNYTCAPSNARPASITV------HVLR 303
                ||::.|:|.|:.:..|..|.|..:.|      ....|...|.:|.|.:..|      ..|:
  Rat   313 ----PSASAYLTVQYPARVLNMPPVIYVPV------GIHGYIRCPVDAEPPATVVKWNKDGRPLQ 367

  Fly   304 GEKT---AAMQHANRSILDTETNGNGTFGLITLGGLNGTSGVTLAGGIL-----YFSGL------ 354
            .||.   ..|:..:..|.:......||:..:....| ||.|.:....::     ||:.|
  Rat   368 VEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTL-GTMGQSAPARLVLKDPPYFTVLPGWEYR 431

  Fly   355 ------FLLMGAVVFDRFSLAATHKV 374
                  .|:..|...|.|.:....||
  Rat   432 QEAGRELLIPCAAAGDPFPVITWRKV 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	22/77 (29%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	19/69 (28%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	3/11 (27%)
		I-set	139..225	CDD:369462	23/100 (23%)
		Ig	229..321	CDD:386229	20/122 (16%)
		Ig	<353..414	CDD:386229	12/61 (20%)
		Ig	438..502	CDD:319273	6/20 (30%)
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900