DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and Fas2

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	65/314 - (20%)
Similarity:	112/314 - (35%)	Gaps:	65/314 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 NTLQSQFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEH 100
            |..::|:.|.....|:.         |.||.:...|:.|:|..|        ...:::.:::|:.
  Fly   142 NAPENQYPTLGQDYVVM---------CEVKADPNPTIDWLRNGD--------PIRTTNDKYVVQT 189

  Fly   101 TRHMGHWSLRIKAVREEDRGFYECQLSIYPTQSIVIELKIVEAV--AEISSAP-ELHIDETSTLR 162
            .      .|.|:.|:|.|.|.|.|:.::..|..::.....||..  .||.|.| .|...|.....
  Fly   190 N------GLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFA 248

  Fly   163 LECKLKRATENPAFVFWYHDSKMINYDSQGGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESS 227
            ..| ..|....|. :.|..|:..:|..:...|      |.|||:|....||.:.....|....:.
  Fly   249 ANC-TARGKPVPE-ISWIRDATQLNVATADRF------QVNPQTGLVTISSVSQDDYGTYTCLAK 305

  Fly   228 N--GVLNSLLGSSDAIKAPAANVPSSTPYMTQQHQSAYLLNPSVSVLTVK-------QVNFRHAG 283
            |  ||::.....:..::.....:.:.|...|::           ..:|.:       .:.||..|
  Fly   306 NRAGVVDQKTKLNVLVRPQIYELYNVTGARTKE-----------IAITCRAKGRPAPAITFRRWG 359

  Fly   284 ---NYTCAPSNARPASI---TVHVLRGEKTAAMQHANRSILDTETNGNGTFGLI 331
               .||....:..|..|   .....|||.|..::.:|     .|.:.:|.:..|
  Fly   360 TQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISN-----AERSDDGLYQCI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	17/76 (22%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	15/69 (22%)
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653	21/104 (20%)
		IGc2	152..209	CDD:197706	17/79 (22%)
		I-set	230..319	CDD:254352	24/96 (25%)
		IGc2	243..309	CDD:197706	17/73 (23%)
		IG_like	330..424	CDD:214653	18/95 (19%)
		IGc2	339..412	CDD:197706	16/75 (21%)
		Ig	447..518	CDD:143165
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900