DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr19 and ncam1a

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_009293555.1	Gene:	ncam1a / 30447	ZFINID:	ZDB-GENE-990415-31	Length:	1010	Species:	Danio rerio

Alignment Length:	318	Identity:	69/318 - (21%)
Similarity:	109/318 - (34%)	Gaps:	103/318 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TLQSQFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHT 101
            ::::::...|.|..|.|...||   |........||.|.|         |.:...||:::.:...
Zfish   210 SIRTRYTELNATADINQAVTLA---CHADGYPEPTVKWAR---------GNTELESDEKYSLNED 262

  Fly   102 RHMGHWSLRIKAVREEDRGFYEC-------QLSIYPTQSIVIELKIVEAVAEISSAPELHIDETS 159
            ..    .|.||.|.:.|.|.|:|       :.|...|.::.::.||  ...|..:|.||  :|..
Zfish   263 GS----ELTIKDVNKLDEGDYKCIARNKAGERSEEVTLNVFVQPKI--TFLENQTASEL--EEQI 319

  Fly   160 TLRLECKLKRATENPA-FVFW-------------------YHDS------------------KMI 186
            ||..|     ||.:|. .:.|                   .|.|                  |.:
Zfish   320 TLTCE-----ATGDPTPNIIWSFGRRVFTENEQASWTRPEKHKSLDGNVVVRSDARVSSLTLKYV 379

  Fly   187 NYDSQGGFVVT---SIGQ---------------SNPQSGQFYRSSPANKSRATMPMESSNGVLNS 233
            .:...|.::.|   ||||               ..||:...:..:|||.:...:....:     |
Zfish   380 QFTDAGQYLCTARNSIGQDIQSMYLEVRYAPKIQGPQAVFTWEGNPANITCEALAHPGA-----S 439

  Fly   234 LLGSSDAIKAPAANVPSSTPYMTQQHQSAYLLNPSVSVLTVKQVNFRHAGNYTCAPSN 291
            :|...|..:.|:||..:...|.|          |:||.|.|...:....|:|.|..:|
Zfish   440 VLWFRDGQQLPSANTTNVKIYNT----------PTVSFLEVTPDSQNDFGSYNCTATN 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	20/83 (24%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	18/76 (24%)
ncam1a	XP_009293555.1	Ig	20..112	CDD:299845
		I-set	21..111	CDD:254352
		IG_like	121..200	CDD:214653
		IGc2	128..189	CDD:197706
		Ig	208..301	CDD:299845	24/106 (23%)
		IG_like	219..298	CDD:214653	24/94 (26%)
		Ig	300..406	CDD:299845	23/114 (20%)
		IG_like	308..406	CDD:214653	21/104 (20%)
		ig	413..498	CDD:278476	22/90 (24%)
		IG_like	415..498	CDD:214653	22/88 (25%)
		fn3	505..589	CDD:278470
		FN3	624..715	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900