DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and Tyro3

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_058788.1	Gene:	Tyro3 / 25232	RGDID:	3923	Length:	880	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	55/273 - (20%)
Similarity:	93/273 - (34%)	Gaps:	56/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 RVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKA 113
            ::...:|....|.|.|:......:.|:  ||..::     .::|.....:.....:|  .|.:|:
  Rat    41 KMTVSQGQPVKLNCSVEGMDDPDIHWM--KDGAVV-----QNASQVSISISEQNWIG--LLSLKS 96

  Fly   114 VREEDRGFYECQL----SIYPTQSIVIELKIVEAVAEISSAP-ELHIDETSTLRLECKLKRATEN 173
            ....|.|.|.||:    ....:||:.:   .||.|...:..| :|.:......:|.|:.....|
  Rat    97 AERSDAGLYWCQVKDGEETKISQSVWL---TVEGVPFFTVEPKDLAVPPNVPFQLSCEAVGPPE- 157

  Fly   174 PAFVFWYHDSKMINYDSQGGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGVLNSLLGSS 238
            |..:||:...             |.:|  .|.|.....:......|.....|:.|  :..|..|.
  Rat   158 PVTIFWWRGP-------------TKVG--GPASSPSVLNVTGVTQRTEFSCEAHN--IKGLATSR 205

  Fly   239 DAI---KAPAANVPSSTPYMTQQHQSAYLL----NPSVSVLTVKQVNFRHAGN------------ 284
            .||   :||.| .|.:....|....:|.:.    ...:::|....|...||..
  Rat   206 PAIIRLQAPPA-APFNITVTTISSSNASVAWVPGADGLALLHSCTVQVAHAPGEWEALAVVVPVP 269

  Fly   285 -YTCAPSNARPAS 296
             :||...|..||:
  Rat   270 PFTCLLRNLAPAT 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	16/80 (20%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	14/69 (20%)
Tyro3	NP_058788.1	IG_like	39..125	CDD:214653	18/95 (19%)
		IGc2	46..111	CDD:197706	16/73 (22%)
		Ig2_Tyro3_like	131..209	CDD:143226	18/95 (19%)
		IG_like	135..204	CDD:214653	16/86 (19%)
		FN3	215..307	CDD:238020	13/69 (19%)
		fn3	315..396	CDD:278470
		PTKc_Tyro3	498..781	CDD:270659
		Pkinase_Tyr	508..776	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	804..827
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	842..864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910