DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	416	Identity:	83/416 - (19%)
Similarity:	142/416 - (34%)	Gaps:	107/416 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EPKRWHLHLSCFLLLLSSTFSDVGKITSSQNHFGNTLQSQFN-----TKNNTRVI-AQKGGLAIL 60
            |.:.|:   .|.:|:|...:...        |.|:.:....|     |:...:.| |::||...:
Mouse   108 EDQGWY---ECKVLMLDQQYDTF--------HNGSWVHLTINAPPTFTETPPQYIEAKEGGSITM 161

  Fly    61 PCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQ 125
            .|....|....|:|:  |:..||........||             .||.:.:|..||||.|.|:
Mouse   162 TCTAFGNPKPIVTWL--KEGTLLGASAKYQVSD-------------GSLTVTSVSREDRGAYTCR 211

  Fly   126 LSIYPTQSIVIELKIVEAVAEISSAPE-LHIDETSTLRLECKLKRATENPAFVFWYHDSKMINYD 189
            ......:::.....:|:....|.|.|| :.::.:....|.|:.:....|..:. ||...:.:.:.
Mouse   212 AYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYT-WYWQDENVYFQ 275

  Fly   190 S----------QGGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGVLNSLLGSSDAIKAP 244
            :          .|..::..:   .|:....|...|:|.                 ||.|
Mouse   276 NDLKLRVRILIDGTLIIFRV---KPEDAGKYTCVPSNS-----------------LGRS------ 314

  Fly   245 AANVPSSTPYMTQQHQSAYLLNPSVSVLTVKQVNFRHAGNYTCAPSNARPASITV------HVLR 303
                ||::.|:|.|:.:..|..|.|..:.|      ....|...|.:|.|.:..|      ..|:
Mouse   315 ----PSASAYLTVQYPARVLNMPPVIYVPV------GIHGYIRCPVDAEPPATVVKWNKDGRPLQ 369

  Fly   304 GEKT---AAMQHANRSILDTETNGNGTFGLITLGGLNGTSGVTLAGGIL-----YFSGL------ 354
            .||.   ..|:..:..|.:......||:..:....| ||.|.:....::     ||:.|
Mouse   370 VEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTL-GTMGQSAPARLVLKDPPYFTVLPGWEYR 433

  Fly   355 ------FLLMGAVVFDRFSLAATHKV 374
                  .|:..|...|.|.:....||
Mouse   434 QEAGRELLIPCAAAGDPFPVITWRKV 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	22/77 (29%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	19/69 (28%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273	3/11 (27%)
		I-set	141..227	CDD:369462	23/100 (23%)
		Ig	231..323	CDD:386229	20/122 (16%)
		Ig	<355..416	CDD:386229	12/61 (20%)
		Ig	440..504	CDD:319273	6/20 (30%)
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900