DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and ntm

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	80/332 - (24%)
Similarity:	138/332 - (41%)	Gaps:	67/332 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 VIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKR-FLVEHTRHMGHWSLRIKA 113
            |..::|..|||.|.|. |....|:|:.|.  .:|..|....|.|.| .|:.:|:  ..:|:.|:.
Frog    46 VTVRQGDSAILRCTVD-NRVTRVAWLNRS--TILYTGNDKWSIDPRVVLLANTK--SQYSIEIQN 105

  Fly   114 VREEDRGFYEC--QLSIYP-TQSIVIELKIVEAVAEISSAPELHIDETSTLRLECKLKRATENPA 175
            |...|.|.|.|  |...:| |..:.:.:::...:.:|||:  :.::|.|.:.|.| :......|.
Frog   106 VDIYDEGPYTCSVQTDNHPKTSRVHLIVQVPPRIVDISSS--IAVNEGSNVSLIC-IANGRPEPV 167

  Fly   176 FVFWYHDSKMINYDSQGGFV-VTSIGQSNPQSGQFYRSSPAN----------KSRATMP---MES 226
            ..:.|...|...:.|:..:: :|.|  :..||| .|..|.:|          |.....|   :::
Frog   168 VNWRYLSPKARGFVSEDEYLEITGI--TREQSG-IYECSASNDVSAPDVRRVKLTVNYPPYILDA 229

  Fly   227 SNGVLNSLLGSSDAIKAPAANVPSSTPY-------MTQQHQSAYLLN-PSVSVLTVKQVNFRHAG 283
            .|  :.:.||....::..|:.||::..:       ::...:...:.| .::|.:|...|:.:..|
Frog   230 QN--IGAPLGHRGILQCEASAVPAADFFWYKEDKRLSDSWRGVKVENRETISRVTFLNVSEQDYG 292

  Fly   284 NYTCAPSNA---RPASITVH---------VLRGEKTAAMQHANRSILDTETNGNGTFGLITLGGL 336
            ||||...|.   ..|||.:.         :|:.|.|||:         |...|.|...
Frog   293 NYTCMAKNLLGHSNASIILFELFQSTSSPLLQEESTAAL---------TPLKGPGAVH------- 341

  Fly   337 NGTSGVT 343
            :|.||.|
Frog   342 DGNSGST 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	26/79 (33%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	24/72 (33%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	28/91 (31%)
		IG_like	45..133	CDD:214653	28/91 (31%)
		IG_like	143..220	CDD:214653	19/82 (23%)
		IGc2	150..209	CDD:197706	16/62 (26%)
		ig	227..311	CDD:278476	19/85 (22%)
		IG_like	230..311	CDD:214653	19/82 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000