DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr19 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	349	Identity:	91/349 - (26%)
Similarity:	136/349 - (38%)	Gaps:	81/349 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 NTLQSQFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEH 100
            |.|.:||.|.    ...:||....|.|....|.|||:.|:    |..:.:..:..||...|.:.:
Zfish   228 NILMNQFPTD----TYLKKGSTLTLTCTADSNPPATIQWV----FNGVNLPSNAVSSPANFTLNN 284

  Fly   101 TRHMGHWSLRIKAVREEDRGFYEC-----QLSIYPTQSIVIELKIVEAVA--EISSAPELHIDET 158
                         :.|::.|.|.|     |...| ..|.|..:.:||:::  .|||:..|.|...
Zfish   285 -------------LEEKNSGNYTCVAYNAQTKRY-IASRVAFVTVVESLSGTNISSSTSLLIAGN 335

  Fly   159 STLRLECKLKRATENPAFVFWYHDSKMINYDSQGGF----VVTSIGQSNPQSGQFYR---SSPAN 216
            ||:.|.|  ..|......|.|..|.|.:|.||:..|    ...||.:...:....||   .:..|
Zfish   336 STVNLTC--FAAAGRAETVEWVKDGKPLNPDSRIVFSADKTSVSIDKVVKEDRGEYRCLLRNKVN 398

  Fly   217 KSRATMPMESSNGVLNSLLGSSDAIK--------APAANVPSSTPYMTQQHQSAYLLNPSVSVLT 273
            |..|:..::.:.|.....:....|:|        ..|.:||.|| |..:.:.:|  ||.|..|..
Zfish   399 KDEASYNLKINYGPEKVAVQGKHAVKFEDDVELSCTAESVPPST-YTWKLNGTA--LNSSQQVYV 460

  Fly   274 VKQVNFRHAGNYTCAPSNARPASITVHVLRGEKTAAMQHANRSILDTETNGNGTFGLITLGGLNG 338
            ||:...|.:|.|||...|    :||..:   :||.   |.    |...|:|....||
Zfish   461 VKRAKDRDSGIYTCEAFN----NITGKM---DKTT---HK----LAVTTDGKEDTGL-------- 503

  Fly   339 TSGVTLAGGILYFSGLFLLMGAVV 362
             ||..:||         :::|.:|
Zfish   504 -SGGAIAG---------IVIGVIV 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	18/81 (22%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	16/74 (22%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845
		IG_like	33..128	CDD:214653
		Ig	130..222	CDD:299845
		IG_like	149..222	CDD:214653
		I-set	233..315	CDD:254352	24/103 (23%)
		Ig_2	235..315	CDD:290606	22/101 (22%)
		IGc2	335..398	CDD:197706	17/64 (27%)
		Ig_2	427..494	CDD:290606	25/83 (30%)
		IG_like	427..479	CDD:214653	19/58 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910