DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr19 and negr1

DIOPT Version :9

Sequence 1:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:283 Identity:69/283 - (24%)
Similarity:116/283 - (40%) Gaps:42/283 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 GNTLQSQFNTKNNTRVIAQKGGLAILPCVVKVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVE 99
            |.::..|:...:|  ::.::|..|:|.|.:: ...:..:|:.|.  .::..|....|.|.|..:.
 Frog    36 GQSMDFQWPAVDN--LVVRQGETAMLRCFLE-EGASKGAWLNRS--SIIFAGGDKWSVDPRVSIA 95

  Fly   100 HTRHMGHWSLRIKAVREEDRGFYEC--QLSIYP-TQSIVIELKIVEAVAEISSAPELHIDETSTL 161
             |.....:||||:.|...|.|.|.|  |....| |..:.:.:.:...:.:|||  ::.::|.:.:
 Frog    96 -TSSKQEYSLRIQKVDVSDDGPYTCSVQTEHSPRTLQVHLTVHVSPKIYDISS--DMTVNEGTNV 157

  Fly   162 RLECKLKRATENP-AFVFWYHDSKMINYDSQGGFVVTSIGQSNPQSGQFYRSSPAN--------K 217
            .|.|   .||..| ..:.|.|.|........|.: :...|.:..|:|. |..|..|        |
 Frog   158 SLIC---LATGKPEPSISWRHISPSAKQFGSGQY-LDIYGITRDQAGD-YECSAENDVSFPDVKK 217

  Fly   218 SRATMPME------SSNGVLNSLLGSSDAIKAPAANVPS-------STPYMTQQHQSAYLLNPSV 269
            .:.|:...      :..||   .||.:..|:...|.||:       ....:|...:...:.|.:.
 Frog   218 VKVTVNFAPTILEITPTGV---SLGRTGLIRCETAAVPAPVFEWYKGEKKLTNGQRGIRIQNYNT 279

  Fly   270 -SVLTVKQVNFRHAGNYTCAPSN 291
             |:|||..|...|.|||||...|
 Frog   280 RSILTVSNVTEEHFGNYTCVAVN 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 21/78 (27%)
IGc2 55..125 CDD:197706 20/71 (28%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 24/97 (25%)
FR1 44..62 CDD:409353 4/19 (21%)
Ig strand A' 47..53 CDD:409353 1/7 (14%)
Ig strand B 55..63 CDD:409353 3/7 (43%)
CDR1 63..68 CDD:409353 0/5 (0%)
FR2 69..75 CDD:409353 1/5 (20%)
Ig strand C 69..74 CDD:409353 1/4 (25%)
CDR2 76..87 CDD:409353 1/12 (8%)
Ig strand C' 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 12/34 (35%)
Ig strand D 91..98 CDD:409353 2/7 (29%)
Ig strand E 101..107 CDD:409353 3/5 (60%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 0/3 (0%)
Ig strand G 127..136 CDD:409353 2/8 (25%)
FR4 129..136 CDD:409353 1/6 (17%)
Ig_3 140..208 CDD:404760 18/74 (24%)
Ig strand A' 146..151 CDD:409353 2/6 (33%)
Ig strand B 157..164 CDD:409353 2/9 (22%)
Ig strand C 170..175 CDD:409353 1/4 (25%)
Ig strand C' 177..179 CDD:409353 1/1 (100%)
Ig strand E 187..193 CDD:409353 0/6 (0%)
Ig strand F 200..207 CDD:409353 3/7 (43%)
Ig strand G 214..222 CDD:409353 1/7 (14%)
Ig_3 226..302 CDD:404760 21/78 (27%)
putative Ig strand A 226..232 CDD:409353 0/5 (0%)
Ig strand B 242..246 CDD:409353 1/3 (33%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 2/3 (67%)
Ig strand F 295..300 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 46 1.000 Domainoid score I11916
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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