DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lft and lix1l

DIOPT Version :9

Sequence 1:	NP_001188775.1	Gene:	lft / 34405	FlyBaseID:	FBgn0032230	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_005159517.1	Gene:	lix1l / 572161	ZFINID:	ZDB-GENE-060503-777	Length:	355	Species:	Danio rerio

Alignment Length:	243	Identity:	178/243 - (73%)
Similarity:	211/243 - (86%)	Gaps:	2/243 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RVNVVEALQEFWQMKQSRGAELKNGALVIYESIPSNSQPYICFVTLPGGSCFGSFQNCPTKAEAR 88
            ||||||||||||||||||||:|:|||||:||.:|||:.||:|:|:|||||||||||.||||||||
Zfish   111 RVNVVEALQEFWQMKQSRGADLRNGALVVYEMVPSNNPPYVCYVSLPGGSCFGSFQFCPTKAEAR 175

  Fly    89 RSSAKIALMNSVFNEHPSRRISDEFIQKAVQDARTSFKGTSQINEGTESGIGAFRFMLEANKGRT 153
            ||:||||||||||||||||||:|:||:|:|.:|..||.|..:..:...:||||||||||:|||::
Zfish   176 RSAAKIALMNSVFNEHPSRRITDDFIEKSVCEALASFNGNREEADNPSTGIGAFRFMLESNKGKS 240

  Fly   154 MLEFQELMTVFQLLHWNGSLKAMRERHCSRQEVVAHYSNRSLDDEMRSQMALDWIAREHDNPGVI 218
            ||||||||||||||||||||||||||.||||||:||||:|:|||:||:|||.||::|||...|.|
Zfish   241 MLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDMRTQMAADWVSREHTLSGTI 305

  Fly   219 RRELVLAERELETFRMAGRELRFPKEKKDILMIAHNQLGGSALNSATI 266
            .||:...|||||..|:|||||||.|||||||::|..|||||  |:.|:
Zfish   306 NREMAATERELEEARLAGRELRFYKEKKDILLMAVGQLGGS--NTTTL 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lft	NP_001188775.1	LIX1	24..255	CDD:291615	171/230 (74%)
lix1l	XP_005159517.1	LIX1	101..342	CDD:291615	171/230 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	325	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2408
OMA	1	1.010	-	-		QHG50057
OrthoDB	1	1.010	-	-		D1026341at2759
OrthoFinder	1	1.000	-	-		FOG0007988
OrthoInspector	1	1.000	-	-		oto39060
orthoMCL	1	0.900	-	-		OOG6_106706
Panther	1	1.100	-	-	LDO	PTHR31139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5506
SonicParanoid	1	1.000	-	-		X5938
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.010