DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lft and lix1

DIOPT Version :9

Sequence 1:	NP_001188775.1	Gene:	lft / 34405	FlyBaseID:	FBgn0032230	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001313325.1	Gene:	lix1 / 558010	ZFINID:	ZDB-GENE-060526-123	Length:	290	Species:	Danio rerio

Alignment Length:	251	Identity:	133/251 - (52%)
Similarity:	179/251 - (71%)	Gaps:	9/251 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EDRDYR-VNVVEALQEFWQMKQSRGAELKNGALVIYESIPSNSQPYICFVTLPGGSCFGSFQNCP 82
            :||.:: :|||..|.:||:.||:.|..::...||:||||||.|.|:||:||||||||||:|::|.
Zfish     8 DDRAFKDLNVVGMLHKFWEQKQAAGVMMEIENLVVYESIPSPSPPFICYVTLPGGSCFGNFKHCY 72

  Fly    83 TKAEARRSSAKIALMNSVFNEHPSRRISDEFIQKAVQDARTSFKGTSQINEGTESGIGAFRFMLE 147
            :||||||.:|::|||||.|||.|.|||:.|||..:|::|.::..|.........:.|||:..|||
Zfish    73 SKAEARRDAARVALMNSTFNELPCRRITPEFISHSVKEAVSTTSGNIADASDPSTSIGAYCLMLE 137

  Fly   148 ANKGRTMLEFQELMTVFQLLHWNGSLKAMRERHCSRQEVVAHYSNRSLDDEMRSQMALDWIAREH 212
            .|.|:|||||||:|||||||||||:|||.|:..||||||:.:||.:.||:..||.|||||:.:|.
Zfish   138 LNTGKTMLEFQEIMTVFQLLHWNGTLKAFRDMRCSRQEVIQYYSQQRLDERTRSHMALDWLQKEL 202

  Fly   213 DNPGVIRRELVLAERELETFRMAGRELRFPKEKKDILMIAHNQLGGSALNSATIDD 268
            .:||::.:||.||.:||...|..||||||.||||:||.:        ||:.|..:|
Zfish   203 QSPGLLSQELQLAVKELGEARRTGRELRFYKEKKEILSL--------ALSHADAED 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lft	NP_001188775.1	LIX1	24..255	CDD:291615	127/231 (55%)
lix1	NP_001313325.1	LIX1	6..245	CDD:291615	131/244 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CB0Y
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1026341at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106706
Panther	1	1.100	-	-	O	PTHR31139
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.800