DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lft and Lix1l

DIOPT Version :9

Sequence 1:	NP_001188775.1	Gene:	lft / 34405	FlyBaseID:	FBgn0032230	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001156642.1	Gene:	Lix1l / 280411	MGIID:	3036267	Length:	337	Species:	Mus musculus

Alignment Length:	234	Identity:	177/234 - (75%)
Similarity:	205/234 - (87%)	Gaps:	0/234 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RVNVVEALQEFWQMKQSRGAELKNGALVIYESIPSNSQPYICFVTLPGGSCFGSFQNCPTKAEAR 88
            ||||||||||||||||||||:|||||||:||.:||||.||:|:|||||||||||||.||||||||
Mouse    97 RVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEAR 161

  Fly    89 RSSAKIALMNSVFNEHPSRRISDEFIQKAVQDARTSFKGTSQINEGTESGIGAFRFMLEANKGRT 153
            ||:||||||||||||||||||:||||:|:|.:|..||.|..:..:...:||||||||||:|||::
Mouse   162 RSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKS 226

  Fly   154 MLEFQELMTVFQLLHWNGSLKAMRERHCSRQEVVAHYSNRSLDDEMRSQMALDWIAREHDNPGVI 218
            ||||||||||||||||||||||||||.||||||:||||:|:|||::|.||||||::||...||.:
Mouse   227 MLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGAL 291

  Fly   219 RRELVLAERELETFRMAGRELRFPKEKKDILMIAHNQLG 257
            .|||...||||:..|:||:||||.||||||||:|..|||
Mouse   292 SRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLG 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lft	NP_001188775.1	LIX1	24..255	CDD:291615	174/230 (76%)
Lix1l	NP_001156642.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
Lix1l	NP_001156642.1	LIX1	87..328	CDD:373420	174/230 (76%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850564
Domainoid	1	1.000	365	1.000	Domainoid score	I932
eggNOG	1	0.900	-	-		E1_2CB0Y
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2128
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50057
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007988
OrthoInspector	1	1.000	-	-		oto92809
orthoMCL	1	0.900	-	-		OOG6_106706
Panther	1	1.100	-	-	LDO	PTHR31139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5506
SonicParanoid	1	1.000	-	-		X5938
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790