DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and Cts8

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001121688.1	Gene:	Cts8 / 680718	RGDID:	1588248	Length:	333	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	118/320 - (36%)
Similarity:	193/320 - (60%)	Gaps:	22/320 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SSANCKSEFEKFKNNNNRKYLRTY---DEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFA 89
            |..:..||::::|.    ||.:.|   :|.:....:|||.||:::||..|.:.:.:|.::.|.||
  Rat    21 SDPSLDSEWQEWKT----KYEKNYSLEEEGQKRAVWEENMKVVKQHNIEYDQEKKNFTMELNAFA 81

  Fly    90 DMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPESLDWRSKGFITPPYNQLSCGSCYAF 154
            ||:.:.:     |.:.:||........:.:..|:...:|:.:|||.:|::|...||.:|.||:||
  Rat    82 DMTGEEF-----RKMMTNIPVQNLRKKKSIHQPIFRYLPKFVDWRRRGYVTSVKNQGTCNSCWAF 141

  Fly   155 SIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVA 219
            |:|.:|.||:|::||:::|||.|.:||||...||.||..||....|.|:.|.||:..:..|||..
  Rat   142 SVAGAIEGQMFRKTGRLVSLSPQNLVDCSRPEGNHGCHMGSTLYALKYVWSNGGLEAESTYPYEG 206

  Fly   220 RKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCS 284
            ::|.|:::|..|...||.::.: .|.|:|:..||..|||:::.|:||..:|:.|..|||.:|.||
  Rat   207 KEGPCRYLPRRSAARVTGFSTV-ARSEEALMHAVATIGPISVGIDASHVSFRFYRRGIYYEPRCS 270

  Fly   285 SASVNHAMVVIGF--------GKDYWILKNWWGQNWGENGYIRIRKG-VNMCGIANYAAY 335
            |..:||:::|:|:        |:.||::||..|..||.|||:::.:| .|.||||.|..|
  Rat   271 SNRINHSVLVVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMKLARGWNNHCGIATYGFY 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	19/62 (31%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	92/217 (42%)
Cts8	NP_001121688.1	PTZ00203	5..327	CDD:185513	116/315 (37%)
		Inhibitor_I29	29..87	CDD:214853	19/61 (31%)
		Peptidase_C1A	115..331	CDD:239068	92/217 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830