Protein Alignment CG5367 and Ctsb

DIOPT Version :9

• Sequence 1: NP_609387.1
• Gene: CG5367 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_072119.2
• Gene: Ctsb / 64529
• RGDID: 621509
• Length: 339
• Species: Rattus norvegicus
• Alignment Length: 373
• Identity: 87/373 - (23%)
• Similarity: 143/373 - (38%)
• Gaps: 99/373 - (26%)

  Fly     2 WKLIFFGCLCGLNCQIVTSNLSEGNSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKV 66
            |.||...||..|              :||:.|..|....           |:|.:|
  Rat     3 WSLIPLSCLLAL--------------TSAHDKPSFHPLS-----------DDMINY--------- 33

  Fly    67 IEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPESL 131
            |.:.|..::.|:..:.:      |:|   |||   :|..:.:  ....:.|.||.....|:|||.
  Rat    34 INKQNTTWQAGRNFYNV------DIS---YLK---KLCGTVL--GGPKLPERVGFSEDINLPESF 84

  Fly   132 DWRSKGFITPPYNQL----SCGSCYAFSIAESIMGQVFKRT-GKI-LSLSKQQIVDCSVSHGNQG 190
            |.|.:....|...|:    |||||:||...|::..::...| |:: :.:|.:.::.|.......|
  Rat    85 DAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDG 149

  Fly   191 CVGGSLRNTLSYLQS----TGGIMRDQ--DYPYV---------ARKGKCQFVPDLSVVN------ 234
            |.||......::...    :||:....  ..||.         ..:..|....|....|
  Rat   150 CNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAG 214

  Fly   235 ------------VTSWAILPVRDEQAIQAAVTHIGPV--AISINASPKTFQLYSDGIYDDPLCSS 285
                        .||:::..  .|:.|.|.:...|||  |.::.:.   |..|..|:|... ...
  Rat   215 YSTSYKEDKHYGYTSYSVSD--SEKEIMAEIYKNGPVEGAFTVFSD---FLTYKSGVYKHE-AGD 273

  Fly   286 ASVNHAMVVIGFGKD----YWILKNWWGQNWGENGYIRIRKGVNMCGI 329
            ....||:.::|:|.:    ||::.|.|..:||:||:.:|.:|.|.|||
  Rat   274 VMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGI 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	9/59 (15%)
		Peptidase_C1A	128..336	CDD:239068	61/247 (25%)
Ctsb	NP_072119.2	Propeptide_C1	26..65	CDD:285358	12/72 (17%)
		Peptidase_C1A_CathepsinB	81..328	CDD:239111	61/247 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910