DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and Cts6

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_067420.1	Gene:	Cts6 / 58518	MGIID:	1889619	Length:	334	Species:	Mus musculus

Alignment Length:	347	Identity:	119/347 - (34%)
Similarity:	186/347 - (53%)	Gaps:	30/347 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IFFGCLCGLNCQIVTSNLSEGNSSSA---NCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKV 66
            :|...||          |..|:.:.|   |..:|:..:|....:.|....:.:|. ..:|||.::
Mouse     5 LFLAILC----------LGVGSGALALDPNLNAEWHDWKKQYEKSYTMEEEGLRR-AIWEENMRM 58

  Fly    67 IEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANV-PES 130
            |:.||.....|:.:|.||.|.|.|::.:.     ||.:.:|....:....:|:....:.:| |:.
Mouse    59 IKLHNWENSLGKNNFTLKMNEFGDLTPEE-----LRKMMNNFPIWSHKKRKIIRKRAVGDVLPKF 118

  Fly   131 LDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGS 195
            :|||.||::|....|..|.||:||::..:|.||:||:|||:..||.|.:|||:.:.||.||..|.
Mouse   119 VDWRKKGYVTRVRRQKFCNSCWAFAVNGAIEGQMFKKTGKLTPLSVQNLVDCTKTQGNDGCQWGD 183

  Fly   196 LRNTLSYLQSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVA 260
            ......|:.:.||:..:..|||..::|.|::.|..|...:|.:..|| ..|..:..||..|||::
Mouse   184 PYIAYEYVLNNGGLEAEATYPYEGKEGPCRYNPKNSKAEITGFVSLP-ESEDILMEAVATIGPIS 247

  Fly   261 ISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGFGKD--------YWILKNWWGQNWGENGY 317
            .:::||...|..|..|||..|.||:.:||||::|:|:|.:        ||::||.||:.||..||
Mouse   248 AAVDASFNRFSFYDGGIYHQPNCSNNTVNHAVLVVGYGTEGNETDGNKYWLIKNSWGRRWGIGGY 312

  Fly   318 IR-IRKGVNMCGIANYAAYAIV 338
            :: ||...|.||||.||.|.||
Mouse   313 MKIIRDQNNHCGIATYAHYPIV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	16/59 (27%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	87/216 (40%)
Cts6	NP_067420.1	PTZ00203	7..332	CDD:185513	115/341 (34%)
		Inhibitor_I29	29..87	CDD:214853	16/58 (28%)
		Peptidase_C1A	116..332	CDD:239068	87/216 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830