DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and zgc:174153

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001104662.1	Gene:	zgc:174153 / 567623	ZFINID:	ZDB-GENE-080215-7	Length:	336	Species:	Danio rerio

Alignment Length:	351	Identity:	113/351 - (32%)
Similarity:	190/351 - (54%)	Gaps:	29/351 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWKLIFFGCLCGLNCQIVTSNLSEGNSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFK 65
            |:.||...|:         |.:....|........:..:|:.:.:.|.... |:.....:|||.:
Zfish     2 MFALIITLCI---------SAVFTAPSIDIQLDDHWNSWKSQHGKSYHEDV-EVGRRMIWEENLR 56

  Fly    66 VIEEHNQNYKEGQTSFRLKPNIFADMSTDGY---LKGFLRLLKSNIEDSADNMAEIVGSPLMANV 127
            .||:||..|..|..:|::..|.|.||:.:.:   :.|:..      :.:..:...:...|.....
Zfish    57 KIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKH------DPNRTSQGPLFMEPSFFAA 115

  Fly   128 PESLDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCV 192
            |:.:|||.:|::||..:|..||||::||...::.||:|::|||::|:|:|.:||||...|||||.
Zfish   116 PQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCN 180

  Fly   193 GGSLRNTLSYLQSTGGIMRDQDYPYVARKG-KCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHI 256
            ||.:.....|::...|:..:|.|||:||.. .|::.|..:|...|.:..:|..:|.|:..||..:
Zfish   181 GGLMDLAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKSTGFVDIPSGNEPALMNAVAAV 245

  Fly   257 GPVAISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGF--------GKDYWILKNWWGQNWG 313
            |||:::|:||.::.|.|..|||.:..|||:.::||::|:|:        |..|||:||.|...||
Zfish   246 GPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWG 310

  Fly   314 ENGYIRIRKGV-NMCGIANYAAYAIV 338
            :.|||.:.|.. |.||:|..|:|.::
Zfish   311 DKGYIYMAKDKNNHCGVATKASYPLM 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	17/59 (29%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	87/217 (40%)
zgc:174153	NP_001104662.1	Inhibitor_I29	28..86	CDD:214853	17/58 (29%)
zgc:174153	NP_001104662.1	Peptidase_C1	115..335	CDD:278538	88/219 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830