DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and CG6347

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	111/323 - (34%)
Similarity:	174/323 - (53%)	Gaps:	28/323 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 FEKFKNNNNRKYLRTYDEMRSYK--AFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLK 98
            |:.|.....:.|   .||.|.|:  .|.....:|...|:|...|.:.|||..|..|||:.    |
  Fly    38 FDDFLRQTGKVY---SDEERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTR----K 95

  Fly    99 GFLRLLKSNIEDSADNMAE------IVGSPLMANVPESLDWRSKGFITPP-YNQLSCGSCYAFSI 156
            ....||.|.|.:..:....      ...:|..||:||..|||.||.:||| :..:.||:|::|:.
  Fly    96 EIATLLGSKISEFGERYTNGHINFVTARNPASANLPEMFDWREKGGVTPPGFQGVGCGACWSFAT 160

  Fly   157 AESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARK 221
            ..::.|.:|:|||.:.|||:|.:|||:..:||.||.||.......|::..|..:.:: |||...:
  Fly   161 TGALEGHLFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQEYGFEYIRDHGVTLANK-YPYTQTE 224

  Fly   222 GKCQ------FVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDD 280
            .:|:      ..|..|:|.:..:|.:...||:.::..:..:||:|.|:||...:|:.||.|||:|
  Fly   225 MQCRQNETAGRPPRESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYED 289

  Fly   281 PLCSSASVNHAMVVIGF----GKDYWILKNWWGQNWGENGYIRI-RKGVNMCGIANYAAYAIV 338
            ..|:...:||::.|:|:    |:||||:||.:.|||||.|::|| |.....||||:..:|.|:
  Fly   290 EECNQGELNHSVTVVGYGTENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYPIL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	19/61 (31%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	82/219 (37%)
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	20/65 (31%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	82/219 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449287
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750