Protein Alignment CtsL4 and Ctsw

DIOPT Version :10

• Sequence 1: NP_609387.1
• Gene: CtsL4 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001019413.1
• Gene: Ctsw / 293676
• RGDID: 1309354
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 380
• Identity: 104/380 - (27%)
• Similarity: 166/380 - (43%)
• Gaps: 73/380 - (19%)

  Fly     4 LIFFGCLC----GLNCQIVTSNLSEGNSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENF 64
            |.:|..|.    ||:..::|   .:........|..|:.|:...||.|....:..|....|..|.
  Rat     7 LFYFLALLLAGQGLSDSLLT---KDAGPRPLELKEVFKLFQIQFNRSYSNPAEYTRRLGIFAHNL 68

  Fly    65 ----KVIEEHNQNYKEGQTSFRLKPNIFADMSTD--GYLKGFLRLLKSNIEDSADNMAEIVGSPL 123
                ::.||.....:.|||.       |:|::.:  |.|.|..|..:..:     |||:.|.|..
  Rat    69 AQAQRLQEEDLGTAEFGQTP-------FSDLTEEEFGQLYGHQRAPERIL-----NMAKKVKSER 121

  Fly   124 MA-NVPESLDWRS-KGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSH 186
            .. :||.:.|||. |..|:...||.:|..|:|.:.|::|......:|.:.:.:|.|:::||. ..
  Rat   122 WGESVPPTCDWRKVKNIISSIKNQGNCRCCWAIAAADNIQTLWRIKTQQFVDVSVQELLDCD-RC 185

  Fly   187 GNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARK----------GKCQFVPDLSVVNVTSWAIL 241
            || ||.||.:.:....:.:..|:..::|||:...:          .|..::.|.::::
  Rat   186 GN-GCNGGFVWDAYITVLNNSGLASEEDYPFQGHQKPHRCLADKYRKVAWIQDFTMLS------- 242

  Fly   242 PVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIY--DDPLCSSASVNHAMVVIGFGKD---- 300
              .:||.|...:...||:.::||.  |..|.|..|:.  ....|....|||:::::||||:
  Rat   243 --SNEQVIAGYLAIHGPITVTINM--KLLQYYQKGVIKATPSTCDPHLVNHSVLLVGFGKEKGGM 303

  Fly   301 -----------------YWILKNWWGQNWGENGYIRIRKGVNMCGIANYAAYAIV 338
                             ||||||.||..|||.||.|:.:|.|.||||.|...|.|
  Rat   304 QTGTLLSHSRKPRRSTPYWILKNSWGAEWGEKGYFRLYRGNNTCGIAKYPITARV 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL4	NP_609387.1	Inhibitor_I29	36..96	CDD:462410	15/65 (23%)
		Peptidase_C1A	128..336	CDD:239068	70/241 (29%)
Ctsw	NP_001019413.1	Inhibitor_I29	40..96	CDD:214853	15/62 (24%)
		Peptidase_C1	126..356	CDD:425470	71/242 (29%)