Protein Alignment CtsL4 and Ctsl

DIOPT Version :10

• Sequence 1: NP_609387.1
• Gene: CtsL4 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_037288.1
• Gene: Ctsl / 25697
• RGDID: 2448
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 122/347 - (35%)
• Similarity: 199/347 - (57%)
• Gaps: 23/347 - (6%)

  Fly     1 MWKLIFFGCLCGLNCQIVTSNLSEGNSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFK 65
            |..|:....|| |...:.|....:      ...:::.::|:.:.|.|....:|.|. ..:|:|.:
  Rat     1 MTPLLLLAVLC-LGTALATPKFDQ------TFNAQWHQWKSTHRRLYGTNEEEWRR-AVWEKNMR 57

  Fly    66 VIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPES 130
            :|:.||..|..|:..|.::.|.|.||:.:.:     |.:.:...........:...|||..:|::
  Rat    58 MIQLHNGEYSNGKHGFTMEMNAFGDMTNEEF-----RQIVNGYRHQKHKKGRLFQEPLMLQIPKT 117

  Fly   131 LDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGS 195
            :|||.||.:||..||..||||:|||.:..:.||:|.:|||::|||:|.:||||...|||||.||.
  Rat   118 VDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGL 182

  Fly   196 LRNTLSYLQSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVA 260
            :.....|::..||:..::.|||.|:.|.|::..:.:|.|.|.:..:| :.|:|:...|..:||::
  Rat   183 MDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIP-QQEKALMKPVATVGPIS 246

  Fly   261 ISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGFG-------KD-YWILKNWWGQNWGENGY 317
            ::::||..:.|.||.|||.:|.|||..::|.::|:|:|       || ||::||.||:.||.:||
  Rat   247 VAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGY 311

  Fly   318 IRIRKG-VNMCGIANYAAYAIV 338
            |:|.|. .|.||:|..|:|.||
  Rat   312 IKIAKDRNNHCGLATAASYPIV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL4	NP_609387.1	Inhibitor_I29	36..96	CDD:462410	17/59 (29%)
		Peptidase_C1A	128..336	CDD:239068	92/216 (43%)
Ctsl	NP_037288.1	Inhibitor_I29	29..87	CDD:214853	17/58 (29%)
		Peptidase_C1	114..332	CDD:425470	93/218 (43%)