DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and Ctso

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_808330.1	Gene:	Ctso / 229445	MGIID:	2139628	Length:	312	Species:	Mus musculus

Alignment Length:	224	Identity:	79/224 - (35%)
Similarity:	121/224 - (54%)	Gaps:	20/224 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 NVPESLDWRSKGFITPPYNQLSCGSCYAFSIAESI-MGQVFKRTGKILS-LSKQQIVDCSVSHGN 188
            ::|...|||.|..:.|..||..||.|:|||:..:| ..:..:  ||.|. ||.||::|||.:  |
Mouse    98 SLPLRFDWRDKHVVNPVRNQEMCGGCWAFSVVSAIESARAIQ--GKSLDYLSVQQVIDCSFN--N 158

  Fly   189 QGCVGGSLRNTLSYLQSTG-GIMRDQDYPYVARKGKCQFVPD----LSVVNVTSWAILPVRDEQA 248
            .||:|||....|.:|..|. .::.|..||:.|..|:|:..|.    :||.:.:::......||.|
Mouse   159 SGCLGGSPLCALRWLNETQLKLVADSQYPFKAVNGQCRHFPQSQAGVSVKDFSAYNFRGQEDEMA 223

  Fly   249 IQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGFGK----DYWILKNWWG 309
              .|:...||:.:.::|  .::|.|..||.... |||...|||:::.||.:    .||:::|.||
Mouse   224 --RALLSFGPLVVIVDA--MSWQDYLGGIIQHH-CSSGEANHAVLITGFDRTGNTPYWMVRNSWG 283

  Fly   310 QNWGENGYIRIRKGVNMCGIANYAAYAIV 338
            .:||..||..::.|.|:||||:..|...|
Mouse   284 SSWGVEGYAHVKMGGNVCGIADSVAAVFV 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	78/218 (36%)
Ctso	NP_808330.1	Peptidase_C1A	100..305	CDD:239068	76/213 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820