DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and cpr-6

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_741818.1	Gene:	cpr-6 / 180931	WormBaseID:	WBGene00000786	Length:	379	Species:	Caenorhabditis elegans

Alignment Length:	398	Identity:	97/398 - (24%)
Similarity:	150/398 - (37%)	Gaps:	119/398 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWKLIFFGCL-----CGLNCQIVTSNLSEGNSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAF 60
            |..|:|..|:     |..|               .|.:|..:|::|.          |:.|..|.
Worm     1 MKTLLFLSCIVVAAYCACN---------------DNLESVLDKYRNR----------EIDSEAAE 40

  Fly    61 EENFKVIEEHNQNY------KEGQTSFRLKPNIFADMSTDGY------LKGFLRLLKSNIEDSAD 113
            .:...:|:..|:|.      |:.:.|.....|..|.....|.      :||     |.::..:.|
Worm    41 LDGDDLIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKG-----KQHLSKTKD 100

  Fly   114 NMAEIVGSPLMANVPESLD----WRSKGFITPPYNQLSCGSCYAFSIAESIMGQV-FKRTGKI-L 172
                     |..::|||.|    |.....|....:|.|||||:||...|::..:: ....|:: :
Worm   101 ---------LDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQV 156

  Fly   173 SLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKG--------------K 223
            :||...::.|..|.| .||.||.......|....|.:....   |.|..|              |
Worm   157 TLSADDLLSCCKSCG-FGCNGGDPLAAWRYWVKDGIVTGSN---YTANNGCKPYPFPPCEHHSKK 217

  Fly   224 CQFVP---DL---------SVVNVT----------SWAILPVRDE-QAIQAAVTHIGPVAISINA 265
            ..|.|   ||         .|.:.|          ..:...|:|: :|||..:...||:.|:
Worm   218 THFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIA--- 279

  Fly   266 SPKTFQLYSDGI-YDDPLC----SSASVNHAMVVIGFGKD----YWILKNWWGQNWGENGYIRIR 321
                |::|.|.: ||..:.    ......||:.:||:|.|    ||.:.|.|..:|||:|:.||.
Worm   280 ----FEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRIL 340

  Fly   322 KGVNMCGI 329
            :||:.|||
Worm   341 RGVDECGI 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	12/65 (18%)
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	71/254 (28%)
cpr-6	NP_741818.1	Propeptide_C1	44..82	CDD:369701	7/37 (19%)
cpr-6	NP_741818.1	Peptidase_C1A_CathepsinB	106..355	CDD:239111	71/254 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920