DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and F32H5.1

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_506310.1	Gene:	F32H5.1 / 179815	WormBaseID:	WBGene00009347	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	304	Identity:	77/304 - (25%)
Similarity:	117/304 - (38%)	Gaps:	91/304 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 LRLLKSNIEDSADNMAEIVGSP-LMANVPESLD----WRSKGFITPPYNQLSCGSCYAFSIAESI 160
            ::.:|||     |.::|..|:. ::.::|.|.|    |.|...|....:|..|||. |..:|..|
Worm    70 IKFIKSN-----DEVSEKTGNDNVLVDIPSSFDSRQKWPSCSQIGAVRDQSDCGSA-AHLVAVEI 128

  Fly   161 MGQVFKRTGKILS-------LSKQQIVDC-----SVSHGNQGCVGGSLRNTLSYLQS----TGGI 209
            ...   || .|.|       ||.|..:.|     |:.....||.|...::.|.:.|:    |||.
Worm   129 ASD---RT-CIASNGTFNWPLSAQDPLSCCVGLMSICGDGWGCDGSWPKDILKWWQTHGLCTGGN 189

  Fly   210 MRDQ-------DYPYVARKGK--------------CQFVPDLSVVNVTSWAILPVRDEQ------ 247
            ..||       .||...:...              |:   :....|:| |.|...:|:.
Worm   190 YNDQFGCKPYSIYPCDKKYANGTTSVPCPGYHTPTCE---EHCTSNIT-WPIAYKQDKHFGKAHY 250

  Fly   248 -------AIQAAVTHIGPVAISINASPKTFQLYSD------GIYDDPLCSSASVNHAM--VVIGF 297
                   .||..:...|||..|       |.:|.|      |||   :.::......|  .:||:
Worm   251 NVGKKMTDIQIEIMTNGPVIAS-------FIIYDDFWDYKTGIY---VHTAGDQEGGMDTKIIGW 305

  Fly   298 GKD----YWILKNWWGQNWGENGYIRIRKGVNMCGIANYAAYAI 337
            |.|    ||:..:.||.::||||::|..:|||...|.:....|:
Worm   306 GVDNGVPYWLCVHQWGTDFGENGFVRFLRGVNEVNIEHQVLAAL 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	70/273 (26%)
F32H5.1	NP_506310.1	Peptidase_C1A_CathepsinB	93..348	CDD:239111	70/273 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810