DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and cpr-4

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_504682.1	Gene:	cpr-4 / 179053	WormBaseID:	WBGene00000784	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	72/264 - (27%)
Similarity:	103/264 - (39%)	Gaps:	67/264 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 VPESLD----WRSKGFITPPYNQLSCGSCYAFSIAESIMGQ-VFKRTGKILS-LSKQQIVDCSVS 185
            :|.:.|    |.:...|....:|..||||:||:.||:...: .....|.:.: ||.:.::.| .|
Worm    81 IPATFDARTQWPNCMSINNIRDQSDCGSCWAFAAAEAASDRFCIASNGAVNTLLSAEDVLSC-CS 144

  Fly   186 HGNQGCVGGSLRNTLSYLQS----TGGIMRDQDYPYVARKGKCQ---FVPDLSVVNVTSWAILP- 242
            :...||.||...|...||..    |||       .|.|:.| |:   ..|....|...:|...|
Worm   145 NCGYGCEGGYPINAWKYLVKSGFCTGG-------SYEAQFG-CKPYSLAPCGETVGNVTWPSCPD 201

  Fly   243 ---------------------VRDE-------------QAIQAAVTHIGPVAISINASPKTFQLY 273
                                 ..|:             ..|||.:...|||..:.......:| |
Worm   202 DGYDTPACVNKCTNKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEAAFTVYEDFYQ-Y 265

  Fly   274 SDGIYDDPLCSSASVNHAMVVIGFGKD----YWILKNWWGQNWGENGYIRIRKGVNMCGIANYAA 334
            ..|:|......... .||:.::|:|.|    ||::.|.|..|||||||.||.:|.|.|||    .
Worm   266 KTGVYVHTTGQELG-GHAIRILGWGTDNGTPYWLVANSWNVNWGENGYFRIIRGTNECGI----E 325

  Fly   335 YAIV 338
            :|:|
Worm   326 HAVV 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	70/259 (27%)
cpr-4	NP_504682.1	Peptidase_C1A_CathepsinB	82..331	CDD:239111	72/263 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750