Protein Alignment CtsL4 and cpr-8

DIOPT Version :10

• Sequence 1: NP_609387.1
• Gene: CtsL4 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_503384.1
• Gene: cpr-8 / 178613
• WormBaseID: WBGene00021070
• Length: 335
• Species: Caenorhabditis elegans
• Alignment Length: 292
• Identity: 77/292 - (26%)
• Similarity: 119/292 - (40%)
• Gaps: 82/292 - (28%)

  Fly   103 LLKSNIEDSADNMAEIVG---SPLMANVPESLDWRSKG---FITPPYNQLS-CGSCYAFSIAESI 160
            :||:.:.|:|....:|..   |...:::..|.|.|.:.   ...|..|.:| |.:.:||:.|||:
 Worm    49 MLKTLVTDAATIGFKIQNFGVSQANSDLSPSFDARERWPECMSIPQINDISECKTSWAFAAAESM 113

  Fly   161 MGQVFKRTG--KILSLSKQQIVDCSV---SHGNQGCVGGSLRNTLSYLQS----TGGIMRDQ--D 214
            ..::...:|  |...||.::::.|..   |.| :||.||:......|:|.    |||....|  .
 Worm   114 SDRLCINSGGFKNTILSAEELLSCCTGMFSCG-EGCEGGNPFKAWQYIQKHGIPTGGSYESQFGC 177

  Fly   215 YPY-VARKGKCQFVPDLSVVNVTSWAI------------------------------------LP 242
            .|| :...||       :|.|||..|.                                    ||
 Worm   178 KPYSIPPCGK-------TVGNVTYPACTNTTSPTPSCEKKCTSRIGYPIDIDKDRHYGVSVDQLP 235

  Fly   243 VRDEQAIQAAVTHIGPVAISINASPKTFQLYSD------GIYDDPLCSSASVNHAMVVIGF---- 297
             ..:..||:.|...||:       ..||::|.|      |||.. |..:...:.::.:||:
 Worm   236 -NSQIEIQSDVMLNGPI-------QATFEVYDDFLQYTTGIYVH-LTGNKQGHLSVRIIGWGVWQ 291

  Fly   298 GKDYWILKNWWGQNWGENGYIRIRKGVNMCGI 329
            |..||:..|.||:.|||||..|:.:|.|.||:
 Worm   292 GVPYWLCANSWGRQWGENGTFRVLRGTNECGL 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL4	NP_609387.1	Inhibitor_I29	36..96	CDD:462410
		Peptidase_C1A	128..336	CDD:239068	71/264 (27%)
cpr-8	NP_503384.1	Propeptide_C1	24..>40	CDD:462365
		Peptidase_C1A_CathepsinB	79..330	CDD:239111	71/262 (27%)