Protein Alignment CtsL4 and F26E4.3

DIOPT Version :10

• Sequence 1: NP_609387.1
• Gene: CtsL4 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_492593.2
• Gene: F26E4.3 / 172827
• WormBaseID: WBGene00009158
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 384
• Identity: 101/384 - (26%)
• Similarity: 157/384 - (40%)
• Gaps: 75/384 - (19%)

  Fly     9 CLCGLNCQIVTSNLSEGNSSSANCKSEFE---KFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEH 70
            |.|.:.|       ..|.....:|..:||   :.|:..|.:.:............|:|.:....|
 Worm    56 CYCDMFC-------DRGPDGGNDCCPDFEATCRGKDIQNDQRIDGESCSMDGDTKEKNCEKCTCH 113

  Fly    71 NQNYKEGQTSFRLKPNIFADMSTDGY------LKGFL-RLLKSNI---------EDSADNMAEIV 119
            |..:|...|:..::|:|...:.|..|      ...|. |.|...|         |.|..||.||:
 Worm   114 NGFWKCDGTACLIQPDILEKIHTGRYSWSARNYSAFWGRSLSDGIKYRLGTLFPERSVQNMNEIL 178

  Fly   120 GSPLMANVPESLDWRSK--GFITPPYNQLSCGSCYAFS---IAESIMGQVFKRTGKILS-LSKQQ 178
            ..|  ..:||..|.|.|  ..|.|..:|..|||.::.|   |:...:..:.:  |:|.| ||.||
 Worm   179 IKP--RELPEHFDARDKWGPLIHPVADQGDCGSSWSVSTTAISSDRLAIISE--GRINSTLSSQQ 239

  Fly   179 IVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVA----RKGKCQFVPDLSVVN----- 234
            ::.|: .|..:||.||.|.....|::.. |::.|..||||:    ..|.| .:|.....|
 Worm   240 LLSCN-QHRQKGCEGGYLDRAWWYIRKL-GVVGDHCYPYVSGQSREPGHC-LIPKRDYTNRQGLR 301

  Fly   235 -------VTSWAILP----VRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDP------- 281
                   .|::.:.|    ...|:.||..:...|||..:. ...:.|.:|:.|:|...
 Worm   302 CPSGSQDSTAFKMTPPYKVSSREEDIQTELMTNGPVQATF-VVHEDFFMYAGGVYQHSDLAAQKG 365

  Fly   282 LCSSASVNHAMVVIGFGKD--------YWILKNWWGQNWGENGYIRIRKGVNMCGIANY 332
            ..|.|...|::.|:|:|.|        ||:..|.||..|||:||.::.:|.|.|.|.::
 Worm   366 ASSVAEGYHSVRVLGWGVDHSTGKPIKYWLCANSWGTQWGEDGYFKVLRGENHCEIESF 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL4	NP_609387.1	Inhibitor_I29	36..96	CDD:462410	13/62 (21%)
		Peptidase_C1A	128..336	CDD:239068	71/246 (29%)
F26E4.3	NP_492593.2	Somatomedin_B	37..83	CDD:460034	7/33 (21%)
		Peptidase_C1A_CathepsinB	185..428	CDD:239111	71/246 (29%)