Protein Alignment CtsL4 and Ctsl

DIOPT Version :10

• Sequence 1: NP_609387.1
• Gene: CtsL4 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_034114.1
• Gene: Ctsl / 13039
• MGIID: 88564
• Length: 334
• Species: Mus musculus
• Alignment Length: 344
• Identity: 122/344 - (35%)
• Similarity: 199/344 - (57%)
• Gaps: 23/344 - (6%)

  Fly     4 LIFFGCLCGLNCQIVTSNLSEGNSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIE 68
            |:....|| |...:.|....:..|      :|:.::|:.:.|.|....:|.|. ..:|:|.::|:
Mouse     4 LLLLAVLC-LGTALATPKFDQTFS------AEWHQWKSTHRRLYGTNEEEWRR-AIWEKNMRMIQ 60

  Fly    69 EHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPESLDW 133
            .||..|..||..|.::.|.|.||:.:.:     |.:.:...........:...|||..:|:|:||
Mouse    61 LHNGEYSNGQHGFSMEMNAFGDMTNEEF-----RQVVNGYRHQKHKKGRLFQEPLMLKIPKSVDW 120

  Fly   134 RSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRN 198
            |.||.:||..||..||||:|||.:..:.||:|.:|||::|||:|.:||||.:.|||||.||.:..
Mouse   121 REKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDF 185

  Fly   199 TLSYLQSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISI 263
            ...|::..||:..::.|||.|:.|.|::..:.:|.|.|.:..:| :.|:|:..||..:||:::::
Mouse   186 AFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIP-QQEKALMKAVATVGPISVAM 249

  Fly   264 NASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGFGKD--------YWILKNWWGQNWGENGYIRI 320
            :||..:.|.||.|||.:|.|||.:::|.::::|:|.:        ||::||.||..||..|||:|
Mouse   250 DASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKI 314

  Fly   321 RKG-VNMCGIANYAAYAIV 338
            .|. .|.||:|..|:|.:|
Mouse   315 AKDRDNHCGLATAASYPVV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL4	NP_609387.1	Inhibitor_I29	36..96	CDD:462410	18/59 (31%)
		Peptidase_C1A	128..336	CDD:239068	91/216 (42%)
Ctsl	NP_034114.1	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
		Peptidase_C1	114..332	CDD:425470	92/218 (42%)