| Sequence 1: | NP_609384.1 | Gene: | CG5022 / 34398 | FlyBaseID: | FBgn0032225 | Length: | 572 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_116281.2 | Gene: | FRMD5 / 84978 | HGNCID: | 28214 | Length: | 570 | Species: | Homo sapiens |
| Alignment Length: | 583 | Identity: | 190/583 - (32%) |
|---|---|---|---|
| Similarity: | 275/583 - (47%) | Gaps: | 66/583 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 12 YKCTVRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIK 76
Fly 77 QCKEMDPLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALGALIVQEEL 140
Fly 141 GDYNEDVHVGSYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGLETYGIDPH 205
Fly 206 PVKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASREPKKHTVG 270
Fly 271 FKCPTGAACRYLWRCAIEQMLFFTLPNSQSAAVISGGGFFSWGTKFRYTGRTEREILTENINALR 335
Fly 336 EQKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRS---TMSEPLGYGMPNGHFYGHDHGMSD 397
Fly 398 ANGGIQISSLEPVCEEARLRSSNIDG---VNYLASQIGGYAYRDSV------EHSSTESGLT--V 451
Fly 452 NGYD---HPRKHNEARQHGSYSPNLYYGQSDGAVNSSSPADSFLHADPSTRKVKKFRKFHLLHAF 513
Fly 514 VPSVIFVAFAMAG-------TAVFIMESESEA--FEQLRNSPEMLCLRYQYYQPLKEFVLEKL 567 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG5022 | NP_609384.1 | B41 | 13..205 | CDD:214604 | 91/192 (47%) |
| FERM_N | 16..80 | CDD:286467 | 35/63 (56%) | ||
| FERM_M | 108..205 | CDD:278785 | 42/96 (44%) | ||
| FERM_C_FRMD3_FRMD5 | 186..294 | CDD:270013 | 41/107 (38%) | ||
| FA | 308..349 | CDD:285894 | 10/40 (25%) | ||
| FRMD5 | NP_116281.2 | B41 | 19..210 | CDD:214604 | 91/191 (48%) |
| FERM_C_FRMD3_FRMD5 | 191..295 | CDD:270013 | 41/107 (38%) | ||
| Interaction with ROCK1. /evidence=ECO:0000269|PubMed:25448675 | 308..353 | 11/44 (25%) | |||
| FA | 309..354 | CDD:370090 | 11/44 (25%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 344..367 | 7/29 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 385..407 | 3/29 (10%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165151642 | |
| Domainoid | 1 | 1.000 | 76 | 1.000 | Domainoid score | I8986 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3530 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 305 | 1.000 | Inparanoid score | I2647 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D227685at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002996 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41718 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105621 | |
| Panther | 1 | 1.100 | - | - | O | PTHR23280 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R7059 |
| SonicParanoid | 1 | 1.000 | - | - | X1988 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.830 | |||||