Protein Alignment CG5022 and frmd5b

DIOPT Version :9

• Sequence 1: NP_609384.1
• Gene: CG5022 / 34398
• FlyBaseID: FBgn0032225
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_021333528.1
• Gene: frmd5b / 569968
• ZFINID: ZDB-GENE-060810-165
• Length: 571
• Species: Danio rerio
• Alignment Length: 613
• Identity: 186/613 - (30%)
• Similarity: 275/613 - (44%)
• Gaps: 125/613 - (20%)

  Fly    12 YKCTVRLLDDSDVLECEFQPFHKGIYLLEYLCGELEIKEKDYFGLRYVDSSKQRHWLDLSKSIIK 76
            :.|||||||||: ..|..|...||.:|.|.:|..|.:.||||||:|:||..||||||:.||.|.|
Zfish    17 FNCTVRLLDDSE-YTCTVQRDAKGHWLFEQVCQHLNLLEKDYFGIRFVDPDKQRHWLEFSKPITK 80

  Fly    77 QCKEMDPLLFSLRVKFYPADPFRLTGN-ARIMLYQQLKRDLRHGRLYCSLGEAAALGALIVQEEL 140
            |.:...|....|||||||.||..|... .|.:|:.|:||||.||||.|...:||.|.|.|:|.|:
Zfish    81 QMRSQPPYTMCLRVKFYPPDPAALKEEITRYLLFLQIKRDLYHGRLLCKSSDAATLAAFILQAEI 145

  Fly   141 GDYNEDVHVGSYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGLETYGIDPH 205
            |||:...|...|.|..:...:.:|.||::|.|:||....||:...:...||..|:.|||||:|||
Zfish   146 GDYDPGKHPEGYSSKFQFFPKHSERLERRIAEIHKSELTGQSPETSELNFLRKAQTLETYGVDPH 210

  Fly   206 PVKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASREPKKHTVG 270
            |.||..|:..::.....|.......:|....:|||:.|:.||.|.|  |:..|  .:|.:|..:.
Zfish   211 PCKDVSGNTAFLAFTPFGFVVLQGNRRIHFLKWNEVTKLKFEAKTF--HIYAT--HQEDQKIILT 271

  Fly   271 FKCPTGAACRYLWRCAIEQMLFFTLPNSQSAAVISGGGFFSWGTKFRYTGRTEREILTENINALR 335
            :..||..||::||:|.:|...|:....|.....:|....|..|::|||:|:..:|::.::....|
Zfish   272 YFAPTPEACKHLWKCGVENQAFYQFEKSSQVRTVSSSNLFFKGSRFRYSGKVAKEVMEQSAKIRR 336

  Fly   336 EQKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRSTMSEPLGYGMPNGHFYGHDHGMSDANG 400
            |......:....:.|.|:....|       |.||:||:                        ...
Zfish   337 EPPEIHRAGMVPSRSCPSITHGP-------RQSSVPRT------------------------RRR 370

  Fly   401 GIQISSLEPVCEEARLRSSNIDGVNYLASQIGGYAYRDSVEHSSTESGLTVNGYDHPRKHNEARQ 465
            .:.||.:|                       |..:.||| .||:....:: |.....|......:
Zfish   371 AVHISIME-----------------------GLESLRDS-GHSTPVRSVS-NSNSFLRSQGNGAE 410

  Fly   466 HGSYSPNLYYGQSDGAVNSSSPADSFLHA----DPS----------TRKVK-------------- 502
            .||       |.::.:.:|.||:||.|..    |||          .|.::
Zfish   411 GGS-------GTAEFSEDSYSPSDSVLPTPVSNDPSDPAQVRHTNGPRNIQEEGGTEQCSQNQAR 468

  Fly   503 ------KFRKFHL-------------LHAFVPS-----VIFVAFAMAGTAVFIMESESE---AF- 539
                  |.::.||             ::.|:.|     ::.||...|...:.|:.:|||   ||
Zfish   469 PQGVKPKGKRSHLEKSRPTQHSPEEGVNQFICSLARLFLVTVALLFALLLLLIVLTESELDLAFL 533

  Fly   540 EQLRNSPEMLCLRYQYYQPLKEFVLEKL 567
            ..:|.:||.....|:|:.||:.::..||
Zfish   534 RDIRRTPEFQQFHYEYFCPLRRWLACKL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5022	NP_609384.1	B41	13..205	CDD:214604	91/192 (47%)
		FERM_N	16..80	CDD:286467	35/63 (56%)
		FERM_M	108..205	CDD:278785	42/96 (44%)
		FERM_C_FRMD3_FRMD5	186..294	CDD:270013	38/107 (36%)
		FA	308..349	CDD:285894	9/40 (23%)
frmd5b	XP_021333528.1	B41	19..210	CDD:214604	91/191 (48%)
		PH-like	191..294	CDD:327399	37/106 (35%)
		FA	309..>343	CDD:312314	9/33 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586154
Domainoid	1	1.000	77	1.000	Domainoid score	I8774
eggNOG	1	0.900	-	-		E1_KOG3530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	270	1.000	Inparanoid score	I2984
OMA	1	1.010	-	-		QHG47808
OrthoDB	1	1.010	-	-		D227685at33208
OrthoFinder	1	1.000	-	-		FOG0002996
OrthoInspector	1	1.000	-	-		otm25643
orthoMCL	1	0.900	-	-		OOG6_105621
Panther	1	1.100	-	-	O	PTHR23280
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1988
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.810